Protein Alignment Prosbeta2R1 and PSMB7

DIOPT Version :10

• Sequence 1: NP_572267.1
• Gene: Prosbeta2R1 / 31511
• FlyBaseID: FBgn0029812
• Length: 307
• Species: Drosophila melanogaster
• Sequence 2: NP_002790.1
• Gene: PSMB7 / 5695
• HGNCID: 9544
• Length: 277
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 150/263 - (57%)
• Similarity: 197/263 - (74%)
• Gaps: 6/263 - (2%)

  Fly    22 GFNFINCRRN----AELLSKGYEPPKAIKTGTSIVGIIYKDGVILGADTRATEGPIVSDKNCSKI 82
            ||:|.|||||    |:...:||:.||..||||:|.|::||||::||||||||||.:|:|||||||
Human    13 GFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKI 77

  Fly    83 HHLQDHIYCCGAGTAADTEMITLTTSAELDLHRLNTERRVPVVCASMMLRRTLFRYQGHIGAALV 147
            |.:..:||||||||||||:|.|...|:.|:||.|:|.|...||.|:.||::.||||||:||||||
Human    78 HFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGYIGAALV 142

  Fly   148 MGGVDTTGPQLYCIYPCGSNDKIPYAAMGSGTLAAMSVLEHGWKPDLDLEQGKQLVREAISAGVF 212
            :||||.|||.||.|||.||.||:||..||||:||||:|.|..::||::.|:.|.||.|||:||:|
Human   143 LGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIF 207

  Fly   213 NDLGSGSNIDLCVITAKGAVYLRTDTIASEKGERLGKYGIKPNSTMVTS--ISVLSLQVTDERIY 275
            ||||||||||||||:.....:||..|:.::||.|||:|..:..:|.|.:  |:.|.::|.:|.:.
Human   208 NDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKGTTAVLTEKITPLEIEVLEETVQ 272

  Fly   276 AVD 278
            .:|
Human   273 TMD 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2R1	NP_572267.1	proteasome_beta_type_7	49..236	CDD:239732	119/186 (64%)
		Pr_beta_C	240..274	CDD:463597	12/35 (34%)
PSMB7	NP_002790.1	proteasome_beta_type_7	44..232	CDD:239732	120/187 (64%)
		Pr_beta_C	235..271	CDD:463597	12/35 (34%)