DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta2R1 and PSMB3

DIOPT Version :9

Sequence 1:	NP_572267.1	Gene:	Prosbeta2R1 / 31511	FlyBaseID:	FBgn0029812	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_002786.2	Gene:	PSMB3 / 5691	HGNCID:	9540	Length:	205	Species:	Homo sapiens

Alignment Length:	198	Identity:	49/198 - (24%)
Similarity:	88/198 - (44%)	Gaps:	15/198 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 GTSIVGIIYKDGVILGADTR-ATEGPIVSDKNCSKIHHLQDHIYCCGAGTAADTEMITLTTSAEL 111
            |.:::.:..|:.|.:.||.| ..:..:|: .:..||..:.|.:|...||.|.|.:.:.......|
Human     8 GGAVMAMKGKNCVAIAADRRFGIQAQMVT-TDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRL 71

  Fly   112 DLHRLNTERRV-PVVCASMMLRRTLFRYQGHIGAALVMGGVDTTGPQLYCIYPCGSNDKI--PYA 173
            :|:.|...|:: |....||:......:..|......|:.|:|   |:.:..:.| |.|.|  |..
Human    72 NLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLD---PKTFKPFIC-SLDLIGCPMV 132

  Fly   174 A---MGSGTLAAM--SVLEHGWKPDLDLEQGKQLVREAISAGVFNDLGSGSNIDLCVITAKGAVY 233
            .   :.|||.|..  .:.|..|:|::|.:...:.:.:|:...|..|..||..:.:.:| .|..:.
Human   133 TDDFVVSGTCAEQMYGMCESLWEPNMDPDHLFETISQAMLNAVDRDAVSGMGVIVHII-EKDKIT 196

  Fly   234 LRT 236
            .||
Human   197 TRT 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2R1	NP_572267.1	20S_bact_beta	48..241	CDD:163402	49/198 (25%)
		proteasome_beta_type_7	49..236	CDD:239732	46/195 (24%)
		Pr_beta_C	241..274	CDD:289249
PSMB3	NP_002786.2	proteasome_beta_type_3	6..201	CDD:239728	49/198 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810