DRSC/TRiP Functional Genomics Resources

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Protein Alignment Prosbeta2R1 and PSMA1

DIOPT Version :9

Sequence 1:NP_572267.1 Gene:Prosbeta2R1 / 31511 FlyBaseID:FBgn0029812 Length:307 Species:Drosophila melanogaster
Sequence 2:NP_683877.1 Gene:PSMA1 / 5682 HGNCID:9530 Length:269 Species:Homo sapiens


Alignment Length:272 Identity:60/272 - (22%)
Similarity:103/272 - (37%) Gaps:64/272 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 KAIKTGTSIVGIIYKDGVILGADTRATEGPIVSDKNCSKIHHLQDHIYCCGAGTAADTEMITLTT 107
            :|:|.|::.||:..|...:|.|..||........|   ||.|:.:||....||..||..::....
Human    33 EAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQK---KILHVDNHIGISIAGLTADARLLCNFM 94

  Fly   108 SAELDLHRLNTERRVPVV-CASMMLRRTLFRYQGH----IGAALVMGGVDTTGPQLYCIYPCGSN 167
            ..|....|...:|.:||. ..|::..:|....|.:    .|..|::.|.|..||.::...|..:.
Human    95 RQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDDMGPHIFQTCPSANY 159

  Fly   168 DKIPYAAMGSGTLAAMSVLEHGWKPDLD------LEQGKQLVREAISAGVFNDLGSGSNIDLCVI 226
            ......::|:.:.:|.:.||......::      ::.|.:.:||.:.|.  .|| :..|:.:.::
Human   160 FDCRAMSIGARSQSARTYLERHMSEFMECNLNELVKHGLRALRETLPAE--QDL-TTKNVSIGIV 221

  Fly   227 TAKGAVYLRTDTIASEKGERLGKYGIKPNSTMVTSISVLSLQVTDERIYAVDDQQPGTSGVQ--- 288
                                 ||                .|:.|   ||..||..|...|::   
Human   222 ---------------------GK----------------DLEFT---IYDDDDVSPFLEGLEERP 246

  Fly   289 ----LDSQQADE 296
                ..:|.|||
Human   247 QRKAQPAQPADE 258

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prosbeta2R1NP_572267.1 20S_bact_beta 48..241 CDD:163402 44/203 (22%)
proteasome_beta_type_7 49..236 CDD:239732 43/197 (22%)
Pr_beta_C 241..274 CDD:289249 4/32 (13%)
PSMA1NP_683877.1 proteasome_alpha_type_1 12..222 CDD:239718 46/215 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0638
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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