DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta2R1 and psmb10

DIOPT Version :9

Sequence 1:	NP_572267.1	Gene:	Prosbeta2R1 / 31511	FlyBaseID:	FBgn0029812	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001002543.2	Gene:	psmb10 / 436816	ZFINID:	ZDB-GENE-040718-278	Length:	276	Species:	Danio rerio

Alignment Length:	276	Identity:	145/276 - (52%)
Similarity:	191/276 - (69%)	Gaps:	8/276 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 NTSADFVGLRSGFNFINCRRN----AELLSKGYEPPKAIKTGTSIVGIIYKDGVILGADTRATEG 71
            |||..  .|..||:|.|.|||    |.|..|||..|.|.||||:|.|:::|||||||||||||:.
Zfish     3 NTSTK--TLTGGFSFENTRRNAVLEANLSEKGYSAPNARKTGTTIAGLVFKDGVILGADTRATDD 65

  Fly    72 PIVSDKNCSKIHHLQDHIYCCGAGTAADTEMITLTTSAELDLHRLNTERRVPVVCASMMLRRTLF 136
            .:|:||||.|||::..:|||||||.|||.|:.|...|:.::||.|:|.|...|...:..|::.||
Zfish    66 MVVADKNCMKIHYIAPNIYCCGAGVAADAEVTTQMMSSNVELHSLSTGRPPLVAMVTRQLKQMLF 130

  Fly   137 RYQGHIGAALVMGGVDTTGPQLYCIYPCGSNDKIPYAAMGSGTLAAMSVLEHGWKPDLDLEQGKQ 201
            |||||||::|::||||..|.|||.:||.||.||:|:..||||..:|:||.|..:||:::||:.||
Zfish   131 RYQGHIGSSLIVGGVDVNGAQLYSVYPHGSYDKLPFLTMGSGAASAISVFEDRYKPNMELEEAKQ 195

  Fly   202 LVREAISAGVFNDLGSGSNIDLCVITAKGAVYLRTDTIASEKGERLGKYGIKPNSTMVTS--ISV 264
            |||:||:||:|.|||||||:||||||.|...||||......|.:|.|.|..||.:|.|.|  ::.
Zfish   196 LVRDAITAGIFCDLGSGSNVDLCVITDKKVDYLRTYDQPVHKNQRGGTYRYKPGTTAVLSKTVTP 260

  Fly   265 LSLQVTDERIYAVDDQ 280
            |:|.|.||.::.:|.:
Zfish   261 LTLDVVDESVHVMDTE 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2R1	NP_572267.1	20S_bact_beta	48..241	CDD:163402	110/192 (57%)
		proteasome_beta_type_7	49..236	CDD:239732	107/186 (58%)
		Pr_beta_C	241..274	CDD:289249	14/34 (41%)
psmb10	NP_001002543.2	PRE1	40..224	CDD:223711	107/183 (58%)
		proteasome_beta_type_7	43..231	CDD:239732	108/187 (58%)
		Pr_beta_C	237..270	CDD:289249	14/32 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53608
OrthoDB	1	1.010	-	-		D415498at33208
OrthoFinder	1	1.000	-	-		FOG0001188
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101382
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1020
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.790