DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta2R1 and psma8

DIOPT Version :9

Sequence 1:	NP_572267.1	Gene:	Prosbeta2R1 / 31511	FlyBaseID:	FBgn0029812	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_998331.1	Gene:	psma8 / 406445	ZFINID:	ZDB-GENE-040426-2194	Length:	251	Species:	Danio rerio

Alignment Length:	190	Identity:	52/190 - (27%)
Similarity:	82/190 - (43%)	Gaps:	8/190 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 KAIKTGTSIVGIIYKDGVILGADTRATEGPIVSDKNCSKIHHLQDHIYCCGAGTAADTEMITLTT 107
            :|:|.|::.|||..||.|:||.:.::. ..:..::...||..|.:|:....||..||..::....
Zfish    26 EAVKKGSTAVGIRGKDIVVLGVEKKSV-AKLQEERTVRKICALDEHVCMAFAGLTADARIVINRA 89

  Fly   108 SAELDLHRLNTERRVPV-----VCASMMLRRTLFRYQGHIGAALVMGGVDTTG-PQLYCIYPCGS 166
            ..|...|||..|..|.|     ..|::..|.|....:...|.:.::.|.|..| |:||...|.|:
Zfish    90 RVECQSHRLTVEDPVTVEYITRYIATLKQRYTQSNGRRPFGISALIVGFDYDGTPRLYQTDPSGT 154

  Fly   167 NDKIPYAAMGSGTLAAMSVLEHGWKPDLDLEQGKQLVREAISAGVFNDLGSGSNIDLCVI 226
            .......|:|.........||..: .|..:......::.||.|.:......|.||:|.||
Zfish   155 YHAWKANAIGRSAKTVREFLEKNY-TDEAIASDNDAIKLAIKALLEVVQSGGKNIELAVI 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2R1	NP_572267.1	20S_bact_beta	48..241	CDD:163402	50/185 (27%)
		proteasome_beta_type_7	49..236	CDD:239732	49/184 (27%)
		Pr_beta_C	241..274	CDD:289249
psma8	NP_998331.1	proteasome_alpha_type_7	5..213	CDD:239724	50/188 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900