DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta2R1 and psma6a

DIOPT Version :9

Sequence 1:	NP_572267.1	Gene:	Prosbeta2R1 / 31511	FlyBaseID:	FBgn0029812	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_705941.2	Gene:	psma6a / 171585	ZFINID:	ZDB-GENE-020326-1	Length:	246	Species:	Danio rerio

Alignment Length:	230	Identity:	49/230 - (21%)
Similarity:	87/230 - (37%)	Gaps:	28/230 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 GLRSGFNFINCRRNAELLS---KGYEPPKAIKT----GTSIVGIIYKDGVILGADTRATEGPIVS 75
            |..:||:     |:..:.|   :.|:...|.|.    |.:.|.:..||..:: ...|.....::.
Zfish     4 GSSAGFD-----RHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVV-ITQRKVPDKLLD 62

  Fly    76 DKNCSKIHHLQDHIYCCGAGTAADTEMITLTTSAELDLHRLNTERRVPVVCASMMLRRTLFRYQG 140
            ....:.:..:.::|.|..:|..||:.........|....:......:||   .|:.:|.....|.
Zfish    63 SSTVTHLFRITENIGCVMSGMTADSRSQVQRARYEAANWKYKYGYEIPV---DMLCKRIADISQV 124

  Fly   141 H--------IGAALVMGGVD-TTGPQLYCIYPCGSNDKIPYAAMGSGTLAAMSVLEHGWKPDLD- 195
            :        :|..:::.||| ..|||:|...|.|........|.|.....|.|.||...|..||
Zfish   125 YTQNAEMRPLGCCMIVVGVDEELGPQVYKCDPAGYYCGFKATAAGVKQTEATSFLEKKIKKKLDW 189

  Fly   196 -LEQGKQLVREAISAGVFNDLGSGSNIDLCVITAK 229
             .:|..:.....:|..:..|. ..|.:::.|:|.:
Zfish   190 TFDQTVETAISCLSTVLAIDF-KPSELEIGVVTTE 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2R1	NP_572267.1	20S_bact_beta	48..241	CDD:163402	41/193 (21%)
		proteasome_beta_type_7	49..236	CDD:239732	40/192 (21%)
		Pr_beta_C	241..274	CDD:289249
psma6a	NP_705941.2	PRK03996	6..239	CDD:235192	48/228 (21%)
psma6a	NP_705941.2	proteasome_alpha_type_6	8..220	CDD:239723	46/221 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900