DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12239 and Y6B3B.4

DIOPT Version :9

Sequence 1:	NP_572265.1	Gene:	CG12239 / 31509	FlyBaseID:	FBgn0029810	Length:	650	Species:	Drosophila melanogaster
Sequence 2:	NP_001364617.1	Gene:	Y6B3B.4 / 189368	WormBaseID:	WBGene00012389	Length:	1311	Species:	Caenorhabditis elegans

Alignment Length:	567	Identity:	107/567 - (18%)
Similarity:	222/567 - (39%)	Gaps:	102/567 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 DRVDSVARDDRGK--------ERREETRVRLDSSLRLEAREARNERRETREERVQPRETREVRVD 125
            ||..||.::...:        ||...|..:..|:..|...::..:..:||....:...:|::..:
Worm   189 DREFSVEKEKEPENPCPLNVYERLSSTSYKRTSTRTLTCPKSAMDLPQTRASMAKMAYSRQLLWE 253

  Fly   126 RRAAREDQLDAREARDERREAREERVQALETREARVDRRESREDREDRRESRADREDRRESREDR 190
                :..|:...:.|..::..::..||...|....:..|:|.|:...::..     .||:.:|
Worm   254 ----KNQQVLVEKLRQRQKREKKSNVQCGFTFADPLAVRKSVEEFNQKKIG-----SRRQGKE-- 307

  Fly   191 LEGREARVQRVEQREARDNQVELREIREIREHRRVTPEERVEQRGIREDRVERHEADEGQRDTRK 255
                         .....:.:||..|.|  |...|.|........:..|........:....|..
Worm   308 -------------TPTTSSNIELHSINE--EPTTVHPASSENSEDVPADPTPSSSISQPPPTTTL 357

  Fly   256 MERRGERESDRRDFETRRLAANERRVERRVEREMSRREERIN---RRDDRTSLDMDLSRRMEREQ 317
            .......|...:|.|.|.:...        |..::..|..:|   ::.:...:|.:|.|::|.|.
Worm   358 FGYVQVPEELEKDDEWREMTEE--------EESLALEENSLNLEIKQAEAMEIDAELERQVEMEA 414

  Fly   318 TERDSEERIESDNHRRAEDRRVERREERENRVRFVFDVRS-------DEDNSRRSEVRKEERDNE 375
            .:.:.|.|....|.:: |:::.|:::|.||..:...::||       ::::..:.::...:..:|
Worm   415 DKLEREHRKNQKNLKK-EEKKQEKQQEMENFFKVFEEIRSLAWSELMEQESVAQYQLHHHQNVHE 478

  Fly   376 --RSVERREE--RNSARRADQDEDLDRVNH--RREANEDVRRAEQESFRRIDLRRVVVDDGARDE 434
              ..|||.|:  ..|.||..:|:|.....|  :::..|::|:..||:                 :
Worm   479 PGTHVERHEKMLSPSRRRGHKDDDDFGKRHEMKQKHAEELRQQLQEA-----------------K 526

  Fly   435 GRRIENSISRREDRQAERTEERVAERRMERVEEEVER-EDSRRVERREIQRRVNGEEFRTNERR- 497
            ..:::...||.|  :....:|.:.||:.:.:|..::| .|:|.....|:.||...::.|..|.:
Worm   527 ASKLKELTSRVE--EVRMKQEALKERKRQLLEARMQRASDNRDKNIMEVIRRAKDDDQRVMEVKF 589

  Fly   498 --EEREDTRREDRV--DTSREEREDTRRVERDGLRREERDEERVDFRRVDLRREERDNQREDLRR 558
              ..:||.:|.:.:  |.|.||::.....||.....|:..::|........||.:...|     |
Worm   590 IATLQEDNKRYELLAKDASVEEKQKQLADERARKHEEKAAKKREQEAAATARRAQAAEQ-----R 649

  Fly   559 ERRVQRREERVDRDHVQRE-------------LSRRAIREPLDERVL 592
            :.|:::..|:.:..|.::|             |:...:.||::...|
Worm   650 QCRIRKLSEQKEIRHGKKENPAPSAPEDMLQYLNSLLLTEPVNSEPL 696

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12239	NP_572265.1	PRK12678	62..>268	CDD:237171	33/206 (16%)
Y6B3B.4	NP_001364617.1	SCAPER_N	27..118	CDD:406813
		PTZ00121	<393..668	CDD:173412	63/299 (21%)
		elast_bind_EbpS	<924..1035	CDD:411220
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	1	0.960