DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15767 and CG5071

DIOPT Version :9

Sequence 1:	NP_572264.1	Gene:	CG15767 / 31508	FlyBaseID:	FBgn0029809	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster

Alignment Length:	470	Identity:	81/470 - (17%)
Similarity:	154/470 - (32%)	Gaps:	147/470 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 AASRVS--TFTERH-HRRVQLSRNKL---------YLQRLSRATSLVHKRPPLMNVKTQSGFDVL 65
            |||.:.  ...||. ||..:|:..|:         ..||..|....||.:..:.....::|..||
  Fly   236 AASMIGWHRLAERDLHRVGRLTGAKMLQVLAHLATQRQRYERQLDQVHFQCRMQAAIQENGMQVL 300

  Fly    66 HEDARIFLERTNANVRLLLNLSKIKRTKGTIDFVEGPP--------------------------- 103
            .      .|..|..:..|    :..|..|.|....|||
  Fly   301 D------FETLNNRIARL----RSHRRPGAIPANVGPPQALILTNYCVYAYWCEMQREMIPPRHR 355

  Fly   104 -------LIPQ---SALP-------QMLQRLDRVQRHNLWLGLRLMRIHERKREGDQRKREGDQQ 151
                   |:|:   :.:|       :.::.||.||:..|          |:.|...|...:|..:
  Fly   356 NLTPDPELLPEPRRAVVPPHFNNSLREVELLDYVQQIEL----------EQFRTLSQPPYDGSHE 410

  Fly   152 KRISEQSQSSNLRCPSTITNRSTLGENEVFNK--------------------YIGWDLDMPDEYF 196
            ...|..|.||.....:.|...:..|..|:..:                    .:...:..||..
  Fly   411 SSSSPNSSSSTNSQSNYIALDTEYGLRELVRQLQQQPQQVQQEQQQQQQQVHQLTHSIYQPDAI- 474

  Fly   197 ELMRLLRPRIV------------------------------LHFGLMD--GRPLGQVVVQLYTEA 229
             |:..:.|:::                              ::|..|:  |...|:|::::.::|
  Fly   475 -LVNSVEPQLIGQQSHDHHRQDGGTSSSVSIVRQPIVHCYPIYFLDMEIAGELAGRVLIEVRSDA 538

  Fly   230 APLVVLQFVRTCLGQRSHEFAVRRIFPRLWVEGYLLS---SCKNSLGEASSLSYRDPMEFDTRVV 291
            ||.:...|......:|.:.:....:| :.|....:::   ..:|..|..|:...|..:..:|.:.
  Fly   539 APRMADNFGALVRHERGYGYRGCTVF-QAWGGESIITGDFESQNGRGGHSAFESRYFLPDETGLP 602

  Fly   292 SHARYAFVLSCAKEYCVHGFPGG----AINFSISFKPLPVARGQRVGFGRVIRGDKVIEAMEAHG 352
            :|.....:....:.....||.|.    .:|...||..:         ||.:::|.::::.:.|.|
  Fly   603 AHRGTVGMRRGQRRQDRSGFVGSQFRLVLNEMRSFTAI---------FGFIVQGIELVDRIAASG 658

  Fly   353 TKNGKISRPLLITHC 367
            ...|:.:...:|.:|
  Fly   659 NALGRPALRSIIRNC 673

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15767	NP_572264.1	cyclophilin	203..370	CDD:294131	33/204 (16%)
CG5071	NP_001303432.1	RING	16..59	CDD:238093
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131	32/170 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900