DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15767 and ppil2

DIOPT Version :9

Sequence 1:	NP_572264.1	Gene:	CG15767 / 31508	FlyBaseID:	FBgn0029809	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_957285.2	Gene:	ppil2 / 393966	ZFINID:	ZDB-GENE-040426-1096	Length:	524	Species:	Danio rerio

Alignment Length:	322	Identity:	61/322 - (18%)
Similarity:	109/322 - (33%)	Gaps:	70/322 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 MNVKTQSGFDVL------HEDARIFLERTNANVRLLLNLSKIKRTKGTIDFVEGPPLIPQSALPQ 112
            :|:||:|..|:|      .:|.....:.||.:...:.|...:|.....:|    |........|.
Zfish   134 LNIKTKSYKDLLTDEPFTRQDLITLQDPTNLDKFNVSNFFHVKNNMKVLD----PDEEKAKQDPS 194

  Fly   113 MLQRLDRVQRHNLWLGLRLMRIHERKREGDQ----RKREGDQQK------------RISEQSQSS 161
            .     .::..||.....|..:: |..:||:    ..:|.:.:|            |:| .|.:|
Zfish   195 Y-----HLKSTNLETRETLAELY-RDYKGDELLASTMKEPEAKKTDKFNAAHYSTGRVS-ASFTS 252

  Fly   162 NLRCPSTITNRSTLGENEVFNKYI---GWDLDMPDEYFELMRLLRPRIVLHFGLMDGRPLGQVVV 223
            ....|:|......:.::.|..:|:   |:                  :.||..      .|.:.|
Zfish   253 TAMAPATNHEADAIADDAVRYQYVKKKGY------------------VRLHTN------KGDLNV 293

  Fly   224 QLYTEAAPLVVLQFVRTCLGQRSHEFAVRRIFPRLWVEGYLLSSCKNSLGEASSLSYRDPMEFDT 288
            :|:.:..|.....|::.|...........|......::|    ......|......:..|.:.:.
Zfish   294 ELHCDKVPKAGENFIKLCKKGYYDGTVFHRSIRNFMIQG----GDPTGTGTGGESFWGKPFKDEF 354

  Fly   289 RV-VSHARYAFVLSCAKEYCVHGFPGGAINFSISFKPLPVARGQRVGFGRVIRGDKVIEAME 349
            |. :||.... :||.|..    |.......|.|:|:.......:...||||:.|.:.:.|||
Zfish   355 RPNLSHTGRG-ILSMANS----GPNTNKSQFFITFRSCAYLDRKHSVFGRVVGGLETLSAME 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15767	NP_572264.1	cyclophilin	203..370	CDD:294131	30/148 (20%)
ppil2	NP_957285.2	Ubox	42..96	CDD:128780
ppil2	NP_957285.2	cyclophilin_RING	281..440	CDD:238904	30/164 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900