Protein Alignment CG15767 and PPIE

DIOPT Version :10

• Sequence 1: NP_572264.1
• Gene: CG15767 / 31508
• FlyBaseID: FBgn0029809
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_001181936.1
• Gene: PPIE / 10450
• HGNCID: 9258
• Length: 314
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 60/307 - (19%)
• Similarity: 102/307 - (33%)
• Gaps: 88/307 - (28%)

  Fly    65 LHEDARIFLERTNANV----RLLLNLSKIKRTKGTIDFVEGPPLIPQSALPQMLQRLDRVQRHNL 125
            |.|||...::..|.:.    .:.:||:|..|.|      ||      |:.|        |...:.
Human    56 LAEDAAAAIDNMNESELFGRTIRVNLAKPMRIK------EG------SSRP--------VWSDDD 100

  Fly   126 WL----GLRLMRIHERKRE--GDQRKREGDQQKRISEQSQSSNLRCPSTITNRSTLGENEVFNKY 184
            ||    |..|   .|.|.|  .:..|.|..:.:.|:::::|:
Human   101 WLKKFSGKTL---EENKEEEGSEPPKAETQEGEPIAKKARSN----------------------- 139

  Fly   185 IGWDLDMPDEYFELMRLLRPRIVLHFGLMDGRPLGQVVVQLYTEAAPLVVLQFVRTCLGQRSHEF 249
                   |..|.::.             :..:|.|::.:.|.::..|:....|...|..::...|
Human   140 -------PQVYMDIK-------------IGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEKGFGF 184

  Fly   250 ---AVRRIFPRLWVEGYLLSSCKNSLGEASSLSYRDPMEFDTRVVSHARYAFVLSCAKEYCVHGF 311
               :..||.|:...:|   ....|..|......|....:.:..::.|.... :||.|..    |.
Human   185 KGSSFHRIIPQFMCQG---GDFTNHNGTGGKSIYGKKFDDENFILKHTGPG-LLSMANS----GP 241

  Fly   312 PGGAINFSISFKPLPVARGQRVGFGRVIRGDKVIEAME-AHGTKNGK 357
            ......|.::........|:.|.||.|..|..|:..:| |..||..|
Human   242 NTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEVAPDTKASK 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15767	NP_572264.1	Pro_isomerase	218..368	CDD:459694	31/144 (22%)
PPIE	NP_001181936.1	RRM_PPIE	8..82	CDD:409783	6/25 (24%)
		cyclophilin_ABH_like	140..279	CDD:238907	29/159 (18%)