Protein Alignment CG42699 and Cep162

DIOPT Version :10

• Sequence 1: NP_572263.2
• Gene: CG42699 / 31507
• FlyBaseID: FBgn0261610
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_955020.2
• Gene: Cep162 / 382090
• MGIID: 1925343
• Length: 1403
• Species: Mus musculus
• Alignment Length: 1040
• Identity: 190/1040 - (18%)
• Similarity: 369/1040 - (35%)
• Gaps: 349/1040 - (33%)

  Fly    46 ESIFQEVSRLSDSTDMRSVDELLQEAERLIQ---QQLRLGGIVPKLDASGP-------PA----- 95
            :.::.|:.:...|.:    ..||.:.:::.|   .||..|..||.:....|       |:
Mouse   439 DKMYLEILKKKTSVN----PSLLPQDDKMNQTSRSQLGAGEEVPVIGKQVPCKKARSTPSLPKRK 499

  Fly    96 PTKTLGEEAATGGDGSSSSP----QSSPHSSIRLNTRYTHRIEHSP-APLAPKTVAVNGR--VRP 153
            |...|...|.:.|.|..|||    .:....:.:.||: |..:...| :....|...::|.  ::|
Mouse   500 PQSGLYASARSSGYGKPSSPLQLFSALEKKTSKDNTK-TKSVRSIPTSNQFRKREILSGTKLIKP 563

  Fly   154 RSGSKSS----ASPTSVQTPLESSNGCGFAAFV----------------------------DNLP 186
            .:.:|.|    .||.:.:.|.:.|:.    :||                            :...
Mouse   564 AASNKPSPHREGSPATPKRPEDPSDD----SFVQLQTEPLGSYGGNREKELLMLKRAQDAEEKWT 624

  Fly   187 SASVISEES----TPKDMDMENHTAAMAKLQLQQL----QDN----------------------- 220
            .|..:.|:.    ..|:.::||...::.:.|.::|    |:|
Mouse   625 GAQALMEQMKMTFCEKEKELENTVESLKRQQERELFRLNQENYILQAKLSSFEETSRKQRWLQFG 689

  Fly   221 -TDDD------EDTMEEITEAEV--------DAPIFSRAEDTGKEVRSPPERQFKSQGRSYIQPS 270
             |.|.      :...:||.|.|.        :..::::.:|..::.:...||.||.....:.:
Mouse   690 ETSDPLTGEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQNLFSE-- 752

  Fly   271 QPIRPMASYSE---------KAVGSSPKRMVSTLTSPIEQI-ASSVSREH-------------AL 312
                 :||..|         :||.::......:.|..:.:: |:...:.|             ||
Mouse   753 -----LASLKEQMHKNHFLSQAVENTEPTKNQSFTDLLAELRAAQKEKNHLMEDIKRLKQDKQAL 812

  Fly   313 KLEIEQL---QERLKD-----TEERLASVRLQSDSLSQTQRALREHNSRLQEESEMLKLDVQHL- 368
            ::::|::   :::.||     |.|:|..:::..::..|....|::......|..|:|..|...|
Mouse   813 EVDLEKVKRERDQAKDQIAYATGEKLYEIKILEETHKQEVSRLQKRLQWYAENQELLDRDAARLR 877

  Fly   369 --NECANVLRSELQAARRDRGEALQMQRSLRDELEEANQERRRTGEGKEKDSRVIQDLQRQCREM 431
              ||....||.|::..:.:.|             ..|.|:|.|:.| :..|::.||||:||.:||
Mouse   878 EANEETEKLRLEIEKLKTESG-------------SPATQQRLRSKE-RALDAKRIQDLERQVKEM 928

  Fly   432 ERILMRKHPDSVSALIVASKSSGMCPLNDQENVNSRKLLEQRIAQLESDAKEQDRKAQQILANVQ 496
            |.||.|::|:|:.|||:|:.::|     |..:.|:.:.:|:||.:||:|.:.:|.:|::.|..::
Mouse   929 EGILKRRYPNSLPALILAASAAG-----DSVDRNTVEFMERRIKKLEADLEGKDEEAKKSLRTME 988

  Fly   497 ARFNSVQAKYETHIADLETQVLSLQEINTKLNEQIESQVRTLDRYMQKRADRYYNNCTQTEPLEE 561
            .:|..::.:||                     :::|.|.:.| .:.||.|.:...|.
Mouse   989 QQFQKMKIQYE---------------------QRLEEQEQLL-AHRQKEAPQSQRNS-------- 1023

  Fly   562 DDVSVGGGVNHGRATPVSSNTMGTQTQAANGTRDHSTNTIGCPSPALVCQQQHLHQAHGHLHPHA 626
                             ||.....:|:..:....|........:...|.:.|:....|
Mouse  1024 -----------------SSRLKALETELGDIKEAHQITVRKLEAEIDVLKHQNADLEH------- 1064

  Fly   627 PSASSSTSSTANSTPNTSRPNSKQSGGQRRSPLVTAGPSKLPISQSDSTLSLLSHGGGGSKEEAQ 691
                              :.|.|                      .|..|..:..    ..|:||
Mouse  1065 ------------------KKNDK----------------------GDQGLQSIEF----QVEQAQ 1085

  Fly   692 LLSSVRSMRVDLAIKNKAMQRLTRELDECKKTIRKLQRDKEGSGSGSQTGSKLDLR--SQASGGA 754
            ..:.:..:..:||.|.:.:|.||:.::..:|. |::...::...|..:|.:|...:  ::..|.|
Mouse  1086 ARAKLARLNEELAAKGREIQDLTKTVERLQKE-RRMMLSRQIPRSREETAAKRLKKDPNRGHGNA 1149

  Fly   755 MQQRRSSGYDHHHHSDHIPAATESQALKEAQNKYRL------------------------LEADY 795
            ..:.......|.|      ..|:|...:..:..|||                        ||...
Mouse  1150 FPETLDGKLYHPH------TFTDSHISEVLEENYRLRSELEGLILERSKLKMESEAAVCQLENSM 1208

  Fly   796 KTLHDKRLQDLKTLQSAHEREL----------------ASCNETV-------------------- 824
            |.:.|.....:.:|:::||||:                |..|..:
Mouse  1209 KRVKDDAAAHIASLKASHEREIEKLLCQNAIENSSSKVAELNRKIATQEVLLKHFQGQVNELQGK 1273

  Fly   825 -----------RILQQRLNEREEALTTQKRRKVP--VDYYALKAKVSLLERRHSEREERLHMLVE 876
                       .|||:::.:..|.|...|....|  ..:..|:.|:..:|.||.:||:.|..:::
Mouse  1274 QESLAVSQVREEILQKQITKLLEELKEAKENHTPEMKHFMGLERKIKQMEMRHRQREQELQQIIQ 1338

  Fly   877  876
            Mouse  1339  1338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42699	NP_572263.2	Smc	<311..>562	CDD:440809	67/261 (26%)
Cep162	NP_955020.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..46
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..243
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	256..292
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	306..348
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	453..606		33/161 (20%)
		Smc	643..1306	CDD:440809	143/793 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1126..1147		3/20 (15%)