Protein Alignment CG42699 and CEP162

DIOPT Version :9

• Sequence 1: NP_572263.2
• Gene: CG42699 / 31507
• FlyBaseID: FBgn0261610
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_055710.2
• Gene: CEP162 / 22832
• HGNCID: 21107
• Length: 1403
• Species: Homo sapiens
• Alignment Length: 975
• Identity: 187/975 - (19%)
• Similarity: 368/975 - (37%)
• Gaps: 272/975 - (27%)

  Fly    66 ELLQEAERLIQQQLRLGGIVP-KLDASGPP----APTKTLGEEAATGGDGSSSSP-------QSS 118
            :|..|.|..:     :|..|| |...|.||    .|...|.....:.|.|..|||       :..
Human   472 QLSSEEEGAV-----MGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFSTLEKK 531

  Fly   119 PHSSIRLNTRYTHRIEHSPAPLAPKTVAVNGRVRPR-------------SGSKSSASPTS----V 166
            ....| :.::....|..|..|...:.::....::|.             |..|.|.:||.    :
Human   532 TSEDI-IKSKNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSENPTETDSCI 595

  Fly   167 QTPLESSNGCG------------FAAFVDNLPSASVISEE----STPKDMDMENHTAAMAKLQLQ 215
            |...:|...||            .....|....|..:.|:    .:.|:.::||....:.|.|.:
Human   596 QFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKELENKLEELKKQQEK 660

  Fly   216 QL----QDN------TDDDEDT------------------------MEEITEAEV--------DA 238
            :|    |||      ....|:|                        .:||.|.|.        :.
Human   661 ELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQGYQQENE 725

  Fly   239 PIFSRAEDTGKEVRSPPERQFKSQGRSYIQPS---QPIRPMASYSEKAVGSSPKR------MVST 294
            .::::.:|..::.:...||.||.....:.:.:   :.:......|:....|.|.|      :::.
Human   726 RLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQMHKSRFLSQVVEDSEPTRNQNFTDLLAE 790

  Fly   295 L-------TSPIEQIASSVSREHALKLEIEQL---QERLKD-----TEERLASVRLQSDSLSQTQ 344
            |       .|.:|.|......:.||:::.|::   :::.||     |.|:|..:::..::..|..
Human   791 LRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGEKLYEIKILEETHKQEI 855

  Fly   345 RALREHNSRLQEESEMLKLDVQHL---NECANVLRSELQAARRDRGE-ALQMQRSLRDELEEANQ 405
            ..|::......|..|:|..|...|   ||....|:.|::..:.:.|. :::.:..|:|
Human   856 SRLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKD------- 913

  Fly   406 ERRRTGEGKEKDSRVIQDLQRQCREMERILMRKHPDSVSALIVASKSSGMCPLNDQENVNSRKLL 470
                    |..|::.||||:||.:|||.||.|::|:|:.|||:|:.::|     |..:.|:.:.:
Human   914 --------KAADAKKIQDLERQVKEMEGILKRRYPNSLPALILAASAAG-----DTVDKNTVEFM 965

  Fly   471 EQRIAQLESDAKEQDRKAQQILANVQARFNSVQAKYETHIADLETQVLSLQEINTKLNEQIESQV 535
            |:||.:||:|.:.:|..|::.|..::.:|..::.:||..:...|      |.:..|||:....::
Human   966 EKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQE------QLLACKLNQHDSPRI 1024

  Fly   536 RTLD--------------RYMQKRAD--RYYN---NCTQTEPLEEDDVSVGGGVN--HGRATPVS 579
            :.|:              |.::...|  ::.|   :..:.:..:||..|:...|.  |.:|..|.
Human  1025 KALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVR 1089

  Fly   580 SN------------------------TMGTQTQAANGTRDHSTNTIGCPSPALVCQQQHLHQAHG 620
            .|                        .|....|.:.|..:.|         |...::..||.:.|
Human  1090 LNEELAAKKREIQDLSKTVERLQKDRRMMLSNQNSKGREEMS---------AKRAKKDVLHSSKG 1145

  Fly   621 HLHPHAPSASSSTSSTANSTPNTSRPNSKQSGGQRRSPLVTAGPSKL--PISQSDSTLSLLSHGG 683
            :               |||.|.|.                   .|||  |.:.:||.:|.:....
Human  1146 N---------------ANSFPGTL-------------------DSKLYQPHTFTDSHVSEVLQEN 1176

  Fly   684 GGSKEEAQLLSSVRSMRVDLAIKNKAMQRLTRELDECKKTIRKLQRDKEGSGSGSQTGSKLDLRS 748
            ...|.|.:.|.|.::   :|.:|::|:      :::.:.::|:::.|.....:..:...:.::..
Human  1177 YRLKNELEGLISEKN---ELKMKSEAV------MNQFENSMRRVKEDTAAHIASLKASHQREIEK 1232

  Fly   749 QASGGAMQQRRSSGYDHHHHSDHIPAATESQALKEAQNKYRLLEADYKTLHDKRLQDLKTLQSAH 813
            .....|::...|...:.:.     ..||:...::..|::...|::..::|....:::
Human  1233 LLCQNAVENSSSKVAELNR-----KIATQEVLIRHFQSQVNELQSKQESLVVSEVRE-------- 1284

  Fly   814 ERELASCNETVRILQQRLNEREEALTTQKRRKVP--VDYYALKAKVSLLERRHSEREERLHMLVE 876
                       .|||:.:.:..|.|...|....|  ..:..|:.|:..:|.||::||:.|..:::
Human  1285 -----------EILQKEITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQIIQ 1338

  Fly   877  876
            Human  1339  1338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42699	NP_572263.2	FlaC	<316..423	CDD:225888	23/118 (19%)
CEP162	NP_055710.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..42
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	170..231
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	476..504		10/32 (31%)
		SMC_prok_B	<672..1385	CDD:274008	144/769 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28K8R
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto91525
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR34031
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5843
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.030