DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42699 and LOC100497718

DIOPT Version :9

Sequence 1:	NP_572263.2	Gene:	CG42699 / 31507	FlyBaseID:	FBgn0261610	Length:	897	Species:	Drosophila melanogaster
Sequence 2:	XP_031758577.1	Gene:	LOC100497718 / 100497718	-ID:	-	Length:	800	Species:	Xenopus tropicalis

Alignment Length:	857	Identity:	182/857 - (21%)
Similarity:	341/857 - (39%)	Gaps:	246/857 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 DNLPSASVISEES-TPKDMDMENHTAAMAKLQLQQLQDNTDDDED----TMEEITEAEVDAPIFS 242
            |:..|||....:| .|:.::|.:....|. |:||.::...:.|:.    ..||..:.|.:  ...
Frog    20 DSFRSASGFHVDSNAPQSLNMSDAELNMF-LKLQNIEQKLNSDQTHSNILREEFLKKEEE--FLE 81

  Fly   243 RAED--TGKEVRSPPERQFKSQGRSYIQPSQPIRPMASYSEKAVG----SSPKRMVSTLTSPIEQ 301
            :.||  |..||    :.|.:.| .:||..:: :..|...:.|::.    ..||..|:  ...|:|
Frog    82 KIEDLKTKYEV----DLQHRKQ-ENYILLTK-LHAMEDKNIKSINKVNLGDPKDPVT--DEKIQQ 138

  Fly   302 IASSVSRE----HALKLEIEQLQERLKDTE-------------------------ERLASV---- 333
            |...:.::    |..:.|.|:|.:::|:.:                         |:|:.|
Frog   139 IRKEIEKQEKLLHGYQQENERLYQQVKELQIRNKQNEELMFQENQSLKANLLSLREQLSKVTISH 203

  Fly   334 -RLQSDS--------------LSQTQRALREHN-----SRLQEESEMLKLDVQHL---------- 368
             |.|.:|              |...|:  ||.|     ||.:::.:.|::|:..:
Frog   204 QRPQDNSEKCNSQSFTDLLVELRTVQK--REANLLDEISRQKQDKQALEVDLMQMRKERDNAPDV 266

  Fly   369 -----------------NECANVLRSELQ------------AAR-RDRGEALQMQRSLRDEL--E 401
                             .:..|||..:|:            |.| ||..|.:::.:...::|  |
Frog   267 YVSGDKSYEMKMMEETYKQEINVLNKKLKWFAESQELLDKDAYRLRDAYEQIEILKMQVEKLKNE 331

  Fly   402 EANQERRRTGEGKEK--DSRVIQDLQRQCREMERILMRKHPDSVSALIVASKSSGMCPLNDQENV 464
            ..||..::....||:  |::.||||:||.:|||.|:.|:||:|:.||..|:.::..|...|....
Frog   332 TGNQSVQQQKRAKERAADAKHIQDLERQVKEMEGIIKRRHPNSILALTFAAAAAPECDDKDSAKK 396

  Fly   465 NSRKLLEQRIAQLESDAKEQDRKAQQILANVQARFNSVQAKYETHIADLETQVLSLQEIN----- 524
            |:...||:|:.:||:|.:.:|.::::.|..::.:|..|:.:||:.|.:|| ::|:.:.||
Frog   397 NTIAFLERRVKKLETDLESKDDESKKSLRTMEQQFQKVKIQYESRIKELE-ELLTHKLINPPQKP 460

  Fly   525 ----TKLNEQIESQV-------RTLDRYMQKRADRYYNNCTQTEPLEEDDVSVGGGVNHGRATPV 578
                ||. ::.|.::       :|..:.:|::.|.:.......|             |:.|....
Frog   461 FDNSTKA-QKFEDELLICKETHQTTIQNLQRQIDLHRKKNLVLE-------------NNERKKEA 511

  Fly   579 SSNTMGTQTQAANGTRDHST-NTIGCPSPALVCQQQHL------------------------HQA 618
            :.:.:||:.:      :||. :.|...|..|:.::..:                        |..
Frog   512 NLSDIGTKVE------EHSNKDLIAKLSQELIAKRIEIQDLTKTVERLQKERMIMLSVRALAHFC 570

  Fly   619 HGHLHPHAPSASSSTSSTANSTPNTSRPNSKQSGGQRRSPLVTAG----------PSKLPISQSD 673
            .|.|        .|..:.|...|.....:.|.|  |.|:.:...|          |..|...|..
Frog   571 RGRL--------ISPCARALKNPLIKAADKKSS--QARTDISALGKRSIRDNMNFPGTLDEKQYH 625

  Fly   674 STLSLLSHGGGGSKEEAQLLSSVRSMRVDLAIKNKAMQRLTRELDECKKTIRKLQRDKEGSGSGS 738
            .......|......|...|...|..:.:.:..:.:..|.|   |.:.:.||::|:.:      ||
Frog   626 PGTFADIHISDAQAENTALKCEVERLSLKINEQKETFQTL---LSQAENTIKRLKEE------GS 681

  Fly   739 QTGSKLDLRSQASGGAMQQRRSSGYDHHHHSDHIPA---------ATESQALKEAQNKYRLLEAD 794
            :..|.|.|        :.|:........|..||..:         :|:...:|..|.:.:.|:.|
Frog   682 EQASALKL--------LHQKEVEKLICQHAIDHSSSKVAELSSKTSTQEILIKHLQTQVKELQKD 738

  Fly   795 YKTLHDKRLQDLKTLQSAHERELASCNETVRILQQRLNEREEALTTQKRRKVPVDYYALKAKVSL 859
            .::|...|::: :|||          .|.|::|:: |.|.:|..|.:.:     |:.||:.|:..
Frog   739 RESLSVYRIRE-ETLQ----------KEVVKLLEE-LKEAKERYTPEMK-----DFLALEHKIKY 786

  Fly   860 LERRHSEREERL 871
            :|:||.:||:.|
Frog   787 MEKRHLQREQEL 798

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42699	NP_572263.2	FlaC	<316..423	CDD:225888	35/199 (18%)
LOC100497718	XP_031758577.1	SMC_prok_B	<131..>800	CDD:274008	154/737 (21%)
LOC100497718	XP_031758577.1	Smc	<133..448	CDD:224117	74/317 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm49387
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000