DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and AGBL2

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	NP_079059.2	Gene:	AGBL2 / 79841	HGNCID:	26296	Length:	902	Species:	Homo sapiens

Alignment Length:	175	Identity:	38/175 - (21%)
Similarity:	70/175 - (40%)	Gaps:	28/175 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 ADPESDPSGSSSSDMLMLESDSSPAMQLVELPSDITVAESQPETE-------HDTENDQQQPESI 162
            :|.||..|||.||     .||..| :.|..:..::|..:...:.:       ....|:|.|.:::
Human   711 SDIESSTSGSDSS-----LSDGLP-VHLANIADELTQKKKMFKKKKKKSLQTRKQRNEQYQKKNL 769

  Fly   163 EEHVVLMKPASQEAQLEQTVDLATEAAPVPL-NDE----LPEDEESPAATESAVEELEKESEAAM 222
            .:.:.|.:..|::|....|:    :..|... |.|    ||...|:|...|:.:...:|::  .:
Human   770 MQKLKLTEDTSEKAGFASTL----QKQPTFFKNSENSSFLPMKNENPRLNETNLNRRDKDT--PL 828

  Fly   223 DDQVPEESEIQPEQVQPGEYQSESDGEQAETKPEIEAQPEVEAQP 267
            |..:  .:.|.|:  ..|..|::..|......|:.......|..|
Human   829 DPSM--ATLILPK--NKGRMQNKKPGFTVSCSPKRTINSSQEPAP 869

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844
AGBL2	NP_079059.2	GVQW	105..>120	CDD:290611
		M14_AGBL2-3_like	407..666	CDD:133117
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	746..770		3/23 (13%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	796..879		17/80 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900