DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and AGBL5

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	NP_068603.4	Gene:	AGBL5 / 60509	HGNCID:	26147	Length:	886	Species:	Homo sapiens

Alignment Length:	143	Identity:	34/143 - (23%)
Similarity:	53/143 - (37%)	Gaps:	24/143 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 IQPEQVQPGEYQSESDG---EQAETKPEIEAQPEVEAQPEAEAQPEAEPQLEVEPQPEVESQPEV 293
            :.|:.|..|.|:::|.|   .:...||:....|.:..............:|        .||...
Human   292 LNPDGVVRGHYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHVHSRL--------NSQSSS 348

  Fly   294 ESQPEVEAQPEVEPQSEVES----QPEAE-SHSEPETQAEV--EAQPEVESLPEAESQPE----- 346
            |.||.....|:. |.|::|.    |.||: .||.....||.  :.:|..:.|......|:
Human   349 EHQPSSCLPPDA-PVSDLEKANNLQNEAQCGHSADRHNAEAWKQTEPAEQKLNSVWIMPQQSAGL 412

  Fly   347 AESQPEREPEVEA 359
            .||.|:..|..|:
Human   413 EESAPDTIPPKES 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844
AGBL5	NP_068603.4	M14_AGBL5_like	176..568	CDD:199860	34/143 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	344..364		7/20 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	605..734
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	784..848
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810