DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and AgaP_AGAP012498

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	XP_024667099.1	Gene:	AgaP_AGAP012498 / 5668386	VectorBaseID:	AGAP012498	Length:	698	Species:	Anopheles gambiae

Alignment Length:	608	Identity:	122/608 - (20%)
Similarity:	198/608 - (32%)	Gaps:	164/608 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 QDVLVDNMKLTSIPSADSSDM-----------------YMLVPDTVASQLEDTEHVNRNSIEAD- 106
            |.:|.|...|  :.|.||.|:                 |....|:|   |..:||....::.|.
Mosquito     1 QRLLSDTQNL--VRSEDSVDINYAQENATHRSQGTIRQYSKSEDSV---LNGSEHTVNKAVLASF 60

  Fly   107 ------PESDPSGSSSSDMLMLESDSSPAMQL-VEL------------PSDITVAESQPETEHDT 152
                  .::|.:.||..|...|.|..|...|: ||:            ..:.|:..|:|....|.
Mosquito    61 NAPIVVTDNDAAESSDIDSRRLNSSRSYVKQINVEILGESMDHNNGQYLKETTILSSKPAEPCDK 125

  Fly   153 ENDQQQPESIEEHVVLMKPAS-QEAQLEQTVDLATEAAPVPLNDELPEDEESPAATESAVEELEK 216
            .|::::....::.|..:||.. .:.:...|..|:|.             .:....|:...:.|..
Mosquito   126 NNNEKEILITKQEVTSIKPGKVSKLRASTTARLSTR-------------HKGTYTTDKPTQILLT 177

  Fly   217 ESEAAMDDQVPEESEIQPEQV-----QPGEYQSESDGEQAETKPEIEAQPEVEAQP--------- 267
            .:...:..:......:.|.|.     ..|:..|..|.....|.  ||.:..|:.|.
Mosquito   178 TTTTTVGKKSVFSKYLAPFQAGLRLSDSGKKYSNQDCSDDNTL--IEERSVVDVQKNFNIKELFI 240

  Fly   268 ----------EAEAQPEAEPQLEVEPQPEVESQPEVESQPEVE--AQPEVEPQSEVESQPEAESH 320
                      :.:.:...:|....:|...:..||.....|.:.  .||.:|...|...||..| :
Mosquito   241 NNTTPSTRYFDVDTKNIKQPVFAEKPIDRIVKQPVFIENPVLRFIKQPTIEENQEERKQPVVE-N 304

  Fly   321 SEPETQAEVEAQPEVESLPEAESQPEAESQPEREPEVEAEKISDNEVDTTEASLMETLVEGIEDG 385
            |.|..         ::.:.|.......:...:.|..|..:||....|          :||.|
Mosquito   305 SVPLV---------IDRIVEKPIHHIVDRPIKVENNVPVDKIVKTPV----------VVEKI--- 347

  Fly   386 LTAAMDNLVPEELAEASDKQETELESEDQQSPVT-EAIEEQ--AVPE-IEQEKEKEPEQITLADE 446
            :|..:.  :|..:|...|:            ||| |.|.|:  .||. |::..|..||:....:.
Mosquito   348 ITKELK--IPYHVAHILDR------------PVTVEKIVEKPVEVPHYIDRPVESSPERPVAVET 398

  Fly   447 TEQDSAQPSNEEPVEIAPEQHTEAEIAPAKIPEEGKPEEEVQVEEESKPVEESKPEEEIKQQEDA 511
            |.:.:.:.....|:   |.||.              .|:.|||   ..||...|..|:|..
Mosquito   399 TVETNIEKIINRPI---PIQHV--------------IEKHVQV---PVPVTLEKVVEKIID---- 439

  Fly   512 KPEEDDQNYAETQPAVTEVKPEETPADIPVEIPAEVPAEIPAEIPAEVPAEIPAESPAEIAAEVP 576
                        :|....|   |...|.|..:...|...:....|.:||.|||...|.::...:|
Mosquito   440 ------------RPVPYTV---EQIIDRPYPVGKIVEKIVDRPYPVQVPVEIPVHYPVQVPVAIP 489

  Fly   577 AEIPAEIPAEIPAETPAETHAEI 599
            ...|.|....:|...|..||:.|
Mosquito   490 VPYPVEKYITLPLHEPKPTHSII 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844
AgaP_AGAP012498	XP_024667099.1	RNase_E_G	<275..448	CDD:331378	51/248 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910