DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and AgaP_AGAP006207

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	XP_001688824.1	Gene:	AgaP_AGAP006207 / 5667132	VectorBaseID:	AGAP006207	Length:	415	Species:	Anopheles gambiae

Alignment Length:	375	Identity:	129/375 - (34%)
Similarity:	200/375 - (53%)	Gaps:	13/375 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   723 YDGAQVWRIVVQTDKDKRMADELQSKYDGQLWKEVKQEVDYLLKPQVLAAAERHIRAANLSRIVL 787
            |...:|:.|.|.|.:...:....|.......|......|  ::.|.:..|.||.:.....|...:
Mosquito    27 YRDYKVYSIRVDTVEKHNVLKRWQDVRGVDFWDRAGYRV--MIHPSLQEAFERFLNLNAFSYERI 89

  Fly   788 IDNLQRVIEKENPPAEKIAELQNRKGH-RLTWQAYHRLEDIHGFIDYMAKTYPDICSTEIIGYSV 851
            |::::..||.|....::....:...|. .:.::.:....:::.::|.:|:|||::.....||.:.
Mosquito    90 IEDVEATIEAERKYDQEYRRRKAASGRATVDFEHFWTNAEVNAYLDELAQTYPNLVRVATIGTTH 154

  Fly   852 EKRPLKILKISNGN---ARNPGIWIDGGMHAREWISPATVTYIANQLVEGWEDLPEHMRSINWYI 913
            |.||:|.:.||..|   ...|.::||||:|||||....:|.|:.::|||......: |.:.:|.|
Mosquito   155 EGRPIKSITISTNNGVAGSKPVVFIDGGIHAREWAGVMSVLYLIHELVEHSSSYAD-MLNKDWVI 218

  Fly   914 HPVANPDGYEYSHTTDRLWRKNMRAHGRQCPGVDLNRNFGYKWGGKGTSASPCSQTYRGSKAFSE 978
            .|||||||||:|||.:|:||||.......|.|:|||||:.|.|   ..|::.||.:|.|:.||||
Mosquito   219 IPVANPDGYEFSHTDNRMWRKNRFPATILCTGIDLNRNWDYLW---VFSSNACSDSYAGTTAFSE 280

  Fly   979 PETFYISKFISGFPRETFQAYLSFHSYGQYILYPWGYDYQL--TQDRADLDRVARQAGTSITKST 1041
            .||..:.:.:..: ......||:.|:||..||||:|:.:..  ..::|....:..||..:||...
Mosquito   281 LETQALDRVLKQY-GSNIAVYLAVHTYGDMILYPYGHSWPFVPVANQAAHIALGEQARDAITAVG 344

  Fly  1042 GVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIEMGDTGRYGFVLPA 1091
            |.:|.||:||..||.|.|.|||:..|:.|.:||||:|:...||.||.|||
Mosquito   345 GPRYVVGNSAEILYTANGCSDDYVAGVIGARYAYTLELTGGGRNGFDLPA 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	13/66 (20%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	111/276 (40%)
AgaP_AGAP006207	XP_001688824.1	Propep_M14	35..99	CDD:280416	13/65 (20%)
AgaP_AGAP006207	XP_001688824.1	M14_CP_A-B_like	124..415	CDD:199844	111/276 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820