DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and Cpa4

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	NP_001102816.1	Gene:	Cpa4 / 502736	RGDID:	1563619	Length:	421	Species:	Rattus norvegicus

Alignment Length:	385	Identity:	144/385 - (37%)
Similarity:	214/385 - (55%)	Gaps:	24/385 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   722 RYDGAQVWRIVVQTDKDKRMADEL--QSKYDGQLWKE---VKQEVDYLLKPQVLAAAERHIRAAN 781
            ::.|.||:||.|:...:.|...||  ...:...:||.   ..:.||.|:....|...:..:::..
  Rat    20 KFFGDQVFRINVRNGDEIRKLTELVNSDHFKLNVWKSPSTFDRPVDILVPSVSLLPVKSFLKSQG 84

  Fly   782 LSRIVLIDNLQRVIEKENPPAEKIAELQNRKGHR----LTWQAYHRLEDIHGFIDYMAKTYPDIC 842
            |...|.|||||.:::.|:      .|:|:.:|..    ..:.:||..|.|:..:|.:|..:||:.
  Rat    85 LDYSVTIDNLQALLDIED------EEMQHNEGRERSGDFNYGSYHSPEAIYHEMDSIATDFPDLA 143

  Fly   843 STEIIGYSVEKRPLKILKISNGNA--RNPGIWIDGGMHAREWISPATVTYIANQLVEGWEDLP-- 903
            |...||.:.||||:.:||.|.|..  :.|.||::.|:|||||||.||..:.|.::|..::..|
  Rat   144 SRVKIGETFEKRPMYVLKFSTGGGGKKRPAIWLNAGIHAREWISQATAIWTARKIVTDYQKDPAV 208

  Fly   904 -EHMRSINWYIHPVANPDGYEYSHTTDRLWRK-NMRAHGRQCPGVDLNRNFGYKWGGKGTSASPC 966
             ..:..::.::.||||||||.|:...:||||| ..|..|.:|.|.|.|||:...:.|:|.|.:||
  Rat   209 TSILEKMDIFLLPVANPDGYVYTQNQNRLWRKTRSRNPGSRCIGADPNRNWNASFAGEGASNNPC 273

  Fly   967 SQTYRGSKAFSEPETFYISKFISGFPRETFQAYLSFHSYGQYILYPWGYDYQLTQDRADLDRVAR 1031
            |:.|.||...||.|...:..||.  ....|:.::..|||.|.::||:||..:...|..:||.|||
  Rat   274 SEVYHGSHPNSEVEVKSVVDFIQ--KHGNFKCFIDLHSYSQLLMYPYGYSVKKAPDAEELDDVAR 336

  Fly  1032 QAGTSITKSTGVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIEMGDTGRYGFVLPA 1091
            .|..::...:|.||.||.:.||:|||:|.|.|||.. .|||||:|.|:.|||.|||:|||
  Rat   337 SAAKALASLSGTKYQVGPTCTTVYPASGSSVDWAYD-NGIKYAFTFELRDTGHYGFLLPA 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	19/71 (27%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	118/277 (43%)
Cpa4	NP_001102816.1	Propep_M14	28..99	CDD:280416	19/70 (27%)
Cpa4	NP_001102816.1	Peptidase_M14_like	117..419	CDD:299699	118/282 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351589
Domainoid	1	1.000	222	1.000	Domainoid score	I2495
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H56753
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8927
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.650