DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3108 and agbl5

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	XP_017210489.1	Gene:	agbl5 / 445479	ZFINID:	ZDB-GENE-040822-29	Length:	886	Species:	Danio rerio

Alignment Length:	703	Identity:	114/703 - (16%)
Similarity:	193/703 - (27%)	Gaps:	258/703 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SAANEGISPKRIVTIGSLLLVLGLNQVASMSLDRLALERNELPADQQQQQQQDVLVDNMKLTSIP 73
            |..:.|.:|...|..|.|..:|......:.:|.|:.:                     .||  ||
Zfish   246 SRVHPGETPSSFVFNGFLNFILSQEDPRAQTLRRMFV---------------------FKL--IP 287

  Fly    74 SADSSDMYMLVPDTVASQLEDTE----HVNRNSIEADPESDPS-----------------GSSSS 117
                    ||.||.|......|:    ::||..:...|:..||                 |.:|.
Zfish   288 --------MLNPDGVVRGHYRTDSRGVNLNRQYVNPSPDLHPSIYGAKSLMLYHHIHNRLGHASG 344

  Fly   118 DMLMLESDSS--------------------------PAMQLVELPSDITVAES------QPETEH 150
            ..|...:.|:                          |...|.|:|  :.:.||      |.|.||
Zfish   345 SALKTSNQSNTSPPVATPTERERCMNLLNEAERGEGPTFDLSEIP--MQLEESWEKSGVQREAEH 407

  Fly   151 DTENDQQQPESIEEHVVLMKPASQEAQLEQTVDLATEAAPVPLNDELPEDEESPAATESAVEELE 215
            ..||:..|...                       .|.:||   ::::|..|...|..........
Zfish   408 SDENESAQSRG-----------------------ETNSAP---SEQVPPQESGVAYYIDLHGHAS 446

  Fly   216 KESEAAMDDQVPEESEIQPEQVQPGEY-------------------------QSESDGEQAETKP 255
            |.......:.:.|||    :||:...|                         :.:.||:..|...
Zfish   447 KRGCFMYGNNLTEES----QQVENMLYAKLISLNCAHFDFLGCNFSEKNMYARDKRDGQSKEGSG 507

  Fly   256 EIEAQP------------------EVEAQPEA-----EAQPEAEPQLEVEPQPEVESQ----PEV 293
            .:....                  .|...|.|     .|.|...|....:..|||..|    ..|
Zfish   508 RVAIHKAMGLVHSYTLECNYNTGRSVNTIPPACHDNGRATPPPPPAFPPKYTPEVYEQVGRAVAV 572

  Fly   294 ESQPEVEAQP---------------EVEPQSEVESQPEAESHSEPETQAEVEAQPEVESLPEAES 343
            .:....|..|               .......|.:.....|::...|..:..:.|...:|
Zfish   573 AALDMAECNPWPRLVLSEHSSLLNLRASILKHVRNSTGLTSNNRRNTHCKTSSSPPKPAL----- 632

  Fly   344 QPEAESQPEREPEVEAEKISDNEVDTTEASLMETLVEGIEDGLTAAMDNLVPEELAEASDKQETE 408
                           :...|:|.::.|.::   |.|:|                     .:|..:
Zfish   633 ---------------STSASENSLNRTRST---TNVQG---------------------SRQTPQ 658

  Fly   409 LESEDQQSPVTEAIEEQ-----AVPEIEQEKEKEPEQITLADETEQD----SAQPSNEEPVEIAP 464
            |:|....:..|.|....     .|.|.:.::::.|....|.....|.    |.:.|......::|
Zfish   659 LKSSPSFTFGTTAHRPSHRSLGPVRECKAQEKRRPPPPPLPHHHHQQHQRLSVRLSAPVRAPLSP 723

  Fly   465 EQHTEAEIAPAKIPEEGKPEEEVQVEEESKPVEESKPEEEIKQQEDAKPEEDDQNYA-----ETQ 524
            ...:.:..:.............:.:...|.|  |.:|..:||:....:.:......|     :.:
Zfish   724 SSSSSSSSSSPSSSSSAPGPGSISLAGNSCP--EFRPANQIKELRGGRGKGGRSGPAYCHSSQQR 786

  Fly   525 PAVTEVKPEETPADIPVEI----------PAEVPAEIPAEIPAEVPAEIPAES 567
            .|:|..:|.:...||...|          |:.:|  :..|:.:.|   ||..|
Zfish   787 TALTTKEPLQDSLDILTSIEYSRCELQPRPSRIP--VRRELQSSV---IPLSS 834

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844
agbl5	XP_017210489.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900