DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and Cpa5

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	NP_001002808.2	Gene:	Cpa5 / 408212	RGDID:	1303098	Length:	436	Species:	Rattus norvegicus

Alignment Length:	384	Identity:	135/384 - (35%)
Similarity:	221/384 - (57%)	Gaps:	25/384 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   723 YDGAQVWRIVVQTDKDKRMADELQ----SKYDGQLWK-------EVKQEVDYLLKPQVLAAAERH 776
            :.|.||.|::.:.:|...:..:|:    .|.|  .|:       .|...|.:...|.|.|    :
  Rat    37 FTGDQVLRVLAKNEKQLSLLRDLEIQKPQKVD--FWRGPARPSLPVDMRVPFSELPSVKA----Y 95

  Fly   777 IRAANLSRIVLIDNLQRVIEKENPPAEKIAELQNRKGHRLTWQAYHRLEDIHGFIDYMAKTYPDI 841
            :::..|:..|:|.::|.::::|.....:...|: |..:..::.:||.||:|:.:||.....:.::
  Rat    96 LKSHGLAYSVMIKDIQVLLDEERDAMARSRRLE-RSTNGFSYSSYHTLEEIYNWIDNFVAEHSNL 159

  Fly   842 CSTEIIGYSVEKRPLKILKISNGNARNPGIWIDGGMHAREWISPATVTYIANQLVEGWED---LP 903
            .|...||.|.|.|.:.:||.|.|......||||.|:|:||||:.||..:|:.::|..:..   |.
  Rat   160 VSKIHIGKSFENRSILVLKFSTGGPNRTAIWIDTGIHSREWITHATGIWISQKIVNAYSKDHVLK 224

  Fly   904 EHMRSINWYIHPVANPDGYEYSHTTDRLWRKNMRAH-GRQCPGVDLNRNFGYKWGGKGTSASPCS 967
            :.:.:::.:|..|.||||:.::|:.:||||||.... |..|.|||||||:...:||.|::.:|||
  Rat   225 KVLNTMDIFIEIVTNPDGFAFTHSMNRLWRKNKSIQPGIVCVGVDLNRNWRTGFGGNGSNKNPCS 289

  Fly   968 QTYRGSKAFSEPETFYISKFISGFPRETFQAYLSFHSYGQYILYPWGYDYQLTQDRADLDRVARQ 1032
            :||||....||||...|..||:|  ...|:|.:|.|||.|.::||:|:..:...:..:|..:|:.
  Rat   290 ETYRGPAPESEPEVAAIVAFITG--HGNFKAMISIHSYSQMVMYPYGHSLEPVPNHKELFELAKD 352

  Fly  1033 AGTSITKSTGVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIEMGDTGRYGFVLPA 1091
            |..::.|..|::|..||.:||||.|:|.:.|||.. :|||||::.|:.|||:|||:|||
  Rat   353 AVKALYKVHGMEYIFGSISTTLYSASGITVDWAYD-SGIKYAFSFELRDTGQYGFLLPA 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	15/77 (19%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	114/275 (41%)
Cpa5	NP_001002808.2	Propep_M14	48..117	CDD:396700	14/74 (19%)
Cpa5	NP_001002808.2	M14_CPA	134..434	CDD:349442	114/280 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351595
Domainoid	1	1.000	222	1.000	Domainoid score	I2495
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8927
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.650