DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and CG7025

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster

Alignment Length:	387	Identity:	132/387 - (34%)
Similarity:	218/387 - (56%)	Gaps:	13/387 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   722 RYDGAQVWRIVVQTDKDKRMADEL-QSKYDGQLWKEVKQEVDYLLKPQVLAAAERHIRAANLSRI 785
            |||...|:::..:|...:.:..:| :.:.:.:||.|.|.|:..:|.|......|..|:..|::..
  Fly    28 RYDNYSVYKVKFETQAQRSILRKLAEDRENFRLWHEAKDELHLMLSPGAFGELETEIQKTNVTAE 92

  Fly   786 VLIDNLQRVIEKENPPAEKIAELQNRKGHRLTWQAYHRLEDIHGFIDYMAKTYPDICSTEIIGYS 850
            :.|.|:|.:|:     :|:.|.|:..:.....|..|:.|.:|:.::|.:...||.|..:.|:|.|
  Fly    93 LFISNVQELID-----SEEAANLKASRDGTFGWTKYNSLAEIYAWLDDILAAYPTITESFIVGQS 152

  Fly   851 VEKRPLKILKISNGNARNPGIWIDGGMHAREWISPATVTYIANQLVEGWEDLPEHM-RSINWYIH 914
            .|.|.::.:|||. .:.|||:.|:..:||||||:.||.|::.|:.:...::|...: .:.:|||.
  Fly   153 YEGRTIRGIKISY-KSNNPGVLIESNIHAREWITSATATWLINEFLTSTDELVRDLAENHDWYIV 216

  Fly   915 PVANPDGYEYSHTTDRLWRKNMR-AHGRQCPGVDLNRNFGYKW-GGKGTSASPCSQTYRGSKAFS 977
            ||.|.||:.|:|..||:|||..: :....|.|.|.|||:...| ..:|.|::||::.|.|.|.||
  Fly   217 PVLNVDGFVYTHEKDRMWRKTRQPSEISSCIGADPNRNYDSHWMENEGASSNPCAEDYGGPKPFS 281

  Fly   978 EPETFYISKFISGFPRETFQAYLSFHSYGQYILYPWGY-DYQLTQDRADLDRVARQAGTSI-TKS 1040
            |||...:|:|:... ::.....|:||||.|.:|.|:|: ..:...:..|:..||:..|.:: :..
  Fly   282 EPEIQAMSEFVISI-KDKINVLLAFHSYSQLLLSPYGHTKEEFPPNFDDMMEVAKAYGDAVESLP 345

  Fly  1041 TGVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIEMGDTGRYGFVLPARFIQYNGKDGV 1102
            .|..|..||:|..||||:|.:.|||....|::.:||||..|||||||:||...|..|.::.:
  Fly   346 YGTVYRYGSAAGILYPASGATIDWAYNEQGVEISYTIEFRDTGRYGFILPPVHIIPNAEEAL 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	16/67 (24%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	108/287 (38%)
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416	15/66 (23%)
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	108/287 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466951
Domainoid	1	1.000	225	1.000	Domainoid score	I2535
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
	11	10.780