DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3108 and CG3097

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	NP_572259.1	Gene:	CG3097 / 31503	FlyBaseID:	FBgn0029804	Length:	445	Species:	Drosophila melanogaster

Alignment Length:	446	Identity:	189/446 - (42%)
Similarity:	250/446 - (56%)	Gaps:	29/446 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   693 VNASFMQQQPSETDLPKTEEESPFNAHLRRYDGAQVWRIV-VQTDKDKR--MADELQSKYDGQLW 754
            |.||...:.||...|....|..      :|||.||:|||. :.....||  :...|:.|:.|.:|
  Fly    17 VAASLANELPSNLTLLDANEIP------QRYDEAQLWRIYNISEAMQKRVPVGQMLEQKFGGNIW 75

  Fly   755 KEVKQEVDYLLKPQVLAAAERHIRAANLSRIVLIDNLQRVIEKENPPAEKIAELQNRKGHR---- 815
            ||..:.:|..:....|.||...:.|..|...:|..|:|.:|::|  ..|.|.......|.|
  Fly    76 KENSKFLDISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDEE--LLEGIQSSSFGHGRRTKKA 138

  Fly   816 ----LTWQAYHRLEDIHGFIDYMAKTYPDICSTEIIGYSVEKRPLKILKISNGNARNPGIWIDGG 876
                :.|:.||.||.|:.|:..:...:|:|.....||.:.|.|.||:|:||.....|..:|||||
  Fly   139 ARSSMHWKDYHDLETIYSFMREIRTKFPNIVRLYTIGQTAEGRDLKVLRISENPRENKKVWIDGG 203

  Fly   877 MHAREWISPATVTYIANQLVEGWEDLPEHMRSINWYIHPVANPDGYEYSHTTDRLWRKNMRAHGR 941
            :||||||||||||:|..||:..||:.|.|:|.:.|||.||.||||||||.||:||||||.....|
  Fly   204 IHAREWISPATVTFILYQLMSDWENQPAHIRGLTWYIMPVMNPDGYEYSRTTNRLWRKNRSPSRR 268

  Fly   942 -QCPGVDLNRNFGYKWGGKGTSASPCSQTYRGSKAFSEPETFYISKFISGFPRETFQAYLSFHSY 1005
             ||.||||||||...|.|.|:|.:|||.|||||...||.||..:::|::. .:...::||:||||
  Fly   269 AQCSGVDLNRNFDIGWNGYGSSTNPCSDTYRGSAPASERETRAVAEFLAK-RKYNLESYLTFHSY 332

  Fly  1006 GQYILYPWGYDYQLTQDRADLDRVARQAGTSITKSTGVKYTVGSSATTLYPAAGGSDDWAKGIAG 1070
            ||.|:|||.|.....:|.:.|.||:..|...|.:.||..|....:...|..|.||||||::...|
  Fly   333 GQMIVYPWAYKAVKVKDASVLQRVSSLAAERILQKTGTSYRAAVTHEVLGIAGGGSDDWSRAALG 397

  Fly  1071 IKYAYTIEMGDTGRYGFVLPARFIQYNGKDGVTFADTVARAIAQGRGKSVARNSSG 1126
            :||.||||:.|.|.||||||.|||:....:|.|..:|||:||..        :|||
  Fly   398 VKYVYTIELRDRGAYGFVLPPRFIKDTALEGWTVVETVAQAIGP--------SSSG 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	20/69 (29%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	145/291 (50%)
CG3097	NP_572259.1	Propep_M14	64..118	CDD:280416	16/53 (30%)
CG3097	NP_572259.1	M14_CP_A-B_like	148..439	CDD:199844	145/291 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448479
Domainoid	1	1.000	215	1.000	Domainoid score	I2654
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm6426
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
	9	8.850