DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and SPBC337.07c

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	NP_595408.1	Gene:	SPBC337.07c / 2541067	PomBaseID:	SPBC337.07c	Length:	497	Species:	Schizosaccharomyces pombe

Alignment Length:	439	Identity:	118/439 - (26%)
Similarity:	183/439 - (41%)	Gaps:	73/439 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   707 LPKTEEESPFNAHLRRYDGAQVWRIVVQTDKDKRMADELQSKYDGQL--WKEVKQEVDYLLKPQV 769
            :|...||.....||               :::..::|.||......|  |......||..||.:.
pombe    70 IPDYNEEIVVRLHL---------------EEENNLSDILQKAQSQNLDIWDYNFDHVDLRLKEEN 119

  Fly   770 LAAAERHIRAANLSRIVLIDNLQRVI------EKENPPAEKIAELQN-RKGH----------RLT 817
            ....:...|:.     :||:||...:      :..|.|....|.||. ..||          .:.
pombe   120 FDFWKSQYRSD-----ILINNLTETLFESIVPDTTNSPFSTEAFLQAVENGHLNHEMFTSFTDIF 179

  Fly   818 WQAYHRLEDIHGFIDYMAKTYPDICSTEIIGYSVEKRPLKILKISNGNARNPG-----------I 871
            :::|..||.|:.::..||..|.|:.....:|.:.|.|.:..||:   |.|:|.           |
pombe   180 FKSYQNLESINSWLRLMASLYKDLSELVPVGITAEGRTILGLKL---NGRHPSDNGEKIRNKKVI 241

  Fly   872 WIDGGMHAREWISPATVTYIANQLVEGWEDLPEHMRSI----NWYIHPVANPDGYEYSHTTDRLW 932
            .|.||.||||||...:|.|.|.||:..: |...|:|.:    .|...||.|.|||||:.:.||||
pombe   242 IIQGGSHAREWIGIPSVCYAAWQLLAKY-DSDGHVRKLLDKFEWIFIPVLNVDGYEYTWSNDRLW 305

  Fly   933 RKNMR-AHGRQCPGVDLNRNFGYKWGGKGTSASPCSQTYRGSKAFSEPETFYISKFIS---GFPR 993
            .||.: .:..:|.|::|:.|:.:.:.|   :..|||..|.|...|...||..:...|:   ...:
pombe   306 SKNRQPLNNSECFGINLDANWAFGFNG---NIDPCSNEYGGLSPFQANETMALFNLITESLSQEQ 367

  Fly   994 ETFQAYLSFHSYGQYILYPWGYDYQL-TQDRADLDRVARQAGTSITKSTGVKYTVGSSATTLYPA 1057
            :....:|..|||.|.:|:|:.|...| ..|..:.:.:|......:.:.....||. ..|...|..
pombe   368 KKVVGFLDVHSYSQSVLWPYAYTCDLFPPDTENFEELAIGLVKELHRVNSRYYTY-QQACIPYDG 431

  Fly  1058 ------AGGSDDWAKGIAGIKYAYTIEMGDTGRYGFVLPARFIQYNGKD 1100
                  .|.:.||....|.:.:.:.|.:.|.|.||::|||:.|....|:
pombe   432 FHKHYLPGTAIDWVYFAADVAWPFNIRLRDMGDYGYLLPAKQIVPTAKE 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	14/74 (19%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	92/306 (30%)
SPBC337.07c	NP_595408.1	MpaA	42..479	CDD:225421	117/436 (27%)
SPBC337.07c	NP_595408.1	M14_CP_A-B_like_1	180..492	CDD:199869	92/309 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
TreeFam	0	0.000	Not matched by this tool.
	9	8.840