DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and K06A9.1

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	NP_001361994.1	Gene:	K06A9.1 / 180494	WormBaseID:	WBGene00019435	Length:	2596	Species:	Caenorhabditis elegans

Alignment Length:	748	Identity:	140/748 - (18%)
Similarity:	221/748 - (29%)	Gaps:	207/748 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 RIVTIGSLLLVLGLNQVASMSLDRLALERNELPADQQQQQQQDVLVDNMKLTSIPSADSSDMYML 83
            |::|:|........::.:|....|.|.......|::.|.:         ...|..:||:|.:.|.
Worm    42 RVITVGICNSGSEPSKASSFRFKRDATTSCSFDANRDQLK---------NFLSSSAADTSFIVMS 97

  Fly    84 V-----PDTVASQLEDTEHVN------RNSIEADP---ESDPSGSSSSDMLMLESDSSPAMQLVE 134
            .     |.||..:.:..|.:|      ..:|:..|   ..||....:||::..    :|.
Worm    98 YSDKPSPSTVLPRDQAIELLNSMKKDGSKTIQQAPAFASYDPKAYENSDLVFF----TPC----- 153

  Fly   135 LPSDITVAESQPETEHDTENDQQQPESIEEHVVLMKPASQEAQLEQ------TVDLATEAAPV-- 191
             .:|.|..::.......|.|:.|     .:..|::..|..:..:.|      |.::...|..:
Worm   154 -KTDYTGYDADMAAVRTTINNVQ-----TKKYVIVSLAMDQGNMTQKYGDLNTHNIGNNATDITN 212

  Fly   192 PLNDELPEDEESPAATESAVEELEKESEAAMDDQVPEESEIQP-----EQVQPGEYQSESDGEQA 251
            .:|:.|.....:...|.:.:        ......||..:..||     ...||....|.:.....
Worm   213 DINNVLNITATTLGPTTTTI--------TPTTTVVPASTSTQPAPASSPTTQPAPATSPTTQPAP 269

  Fly   252 ETKPEIEAQPEVEAQPEAEAQPEAEPQLEVEPQPEVESQPEVESQPEVEAQPEVEPQSEVESQPE 316
            .|.|  ..||.....|..:..|...|..:..|.....:||...:.|..:..|...|    .:||.
Worm   270 ATSP--TTQPAPATSPTTQPAPATSPTTQPAPATSPTTQPAPATSPTTQPAPATSP----TTQPA 328

  Fly   317 AESHSEPETQAEVEAQPEVESLPEAE--SQPEAESQPEREPEVEAEKISDNEVDTTEASLMETLV 379
            ..  :.|.||......|..:..|...  :||...:.|..:|              |.|:
Worm   329 PA--TSPTTQPAPATSPTTQPTPATSPTTQPTPATSPTTQP--------------TPAT------ 371

  Fly   380 EGIEDGLTAAMDNLVPEELAEASDKQETELESEDQQSPVTEAIEEQAVPEIEQEKEKEPEQITLA 444
                                                ||.|     |..|......:..|    ..
Worm   372 ------------------------------------SPTT-----QPAPATSPTTQPAP----AT 391

  Fly   445 DETEQDSAQPSNEEPVEIAPEQHTEAEIAPAKIPEEGKPEEEVQVEEESKPVEESKPEEEIKQQE 509
            ..|.|.:  |:.....:.||......:.|||..|             .::|...:.|
Worm   392 SPTTQPA--PATSPTTQPAPATSPTTQPAPATSP-------------TTQPAPATSP-------- 433

  Fly   510 DAKPEEDDQNYAETQPA-VTEVKPEETPADIPVEIPAEVPAEIPAEIPAEVPAEIPAESPAEIAA 573
                        .|||| .|....:.||...|...||  ||..|...|:  ||..|...|:..::
Worm   434 ------------TTQPAPATSPTTQPTPGTSPTTQPA--PATSPTTQPS--PATNPTTQPSVSSS 482

  Fly   574 EVPAEIPAEIPAEIPAETPAETHAEIPADVPAQVVAEAPAETPAETPAEVPAEIPSKV-----QD 633
            ......||......||  ||.:....||...:.....|||.:|...||...:.....|     |.
Worm   483 ASTQPAPATSGTTQPA--PATSATTQPAPATSATTQPAPATSPTTQPAPATSATTQSVPVVTTQT 545

  Fly   634 EIQSDSTQAEPQVEKEAQQPE----------KETKPLESSLLTTIIPMV------MPQPQVPSQP 682
            .:.:..|.|.......|..|.          ..:.||.||:.|:.:|:.      .|.....:.|
Worm   546 TMGTSPTTAGISSSPAATSPSTAVTSPSSLGTSSSPLPSSISTSALPIASSSASSSPSAASSTTP 610

  Fly   683 LQVQDSVLNYVNASFMQQQPSETDLPKTEEESP 715
            :.:..|.:          |.|....|.:...||
Worm   611 VVLSSSTI----------QSSSGTFPSSVASSP 633

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844
K06A9.1	NP_001361994.1	PHA03247	<241..534	CDD:223021	80/406 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910