DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and ZK84.1

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	NP_495202.1	Gene:	ZK84.1 / 174008	WormBaseID:	WBGene00022649	Length:	801	Species:	Caenorhabditis elegans

Alignment Length:	850	Identity:	207/850 - (24%)
Similarity:	307/850 - (36%)	Gaps:	176/850 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 KRIVTIGSLLL--VLGLNQVASMSLDR-LALERNELPADQQQQQQQDVLVDNMKLT--SIPSADS 77
            |:..|||...:  ..|:..:..::.|. |.:.:.....::.:|:::|......|.|  ::.||..
Worm    33 KKAKTIGEYAINTPTGIFPIKDINDDNFLDIFKFRPEIEKLRQEERDNAAAAAKSTDAAVNSASV 97

  Fly    78 SDMY--MLVPDTVASQLEDTEHVNRNSIEADPESDPSGSSSSDMLMLESDSSPAMQLVE---LPS 137
            ...|  ..|.|..|...|.|           |.:.|.|::......:|...|     ||   :|.
Worm    98 DTGYGDGAVADVAAPGPEPT-----------PATAPEGAAEPVPTAVEGSGS-----VEGSGIPD 146

  Fly   138 DITVAESQPETEHDT-ENDQQQPESI---EEHVVLMKPASQE-----------AQLEQTVDLATE 187
            ::....:......|. .:|....|::   |..::|..||..:           ::.||....|.|
Worm   147 EVATTVAADSGSGDAPASDNSVTETLTATEPAIILPPPAEPKKIIPPASGYVTSEQEQGAGDAPE 211

  Fly   188 AAPVPLNDELPEDEESPAATESAVEELEKESEAAMDDQVPEESEIQPEQVQPGEYQSESDGEQAE 252
            .|||.        ||:||.|.:|.|.....:||:.....||           |.....::...|.
Worm   212 PAPVV--------EETPAPTPAAEETPAPATEASNAVGTPE-----------GYVDGTANAASAV 257

  Fly   253 TKPEIEA---QPEVEAQPEAEAQPEAEPQLEVEPQPEVESQPEVESQPEVEAQPEVEPQSEVESQ 314
            .:|.:|.   .|..|..|......|..|    .|.|..|..|..|:   |.|.||. ..|...:.
Worm   258 AEPAVETPAPAPAAEETPAPATSSEEAP----APAPTAEETPAPET---VSAAPEA-ANSYDSAG 314

  Fly   315 PEAESHSEPETQAEVEAQPEVESLPEAESQPEAESQPEREPEVEAEKISDNEVDTTEASLMETLV 379
            .:|.:...|.::|...|.| .:|...|::..........|...|:.:....::..||.:...::.
Worm   315 GDAATAPAPSSEAADAAAP-TDSAASADTTAALVDTSSSEHAAESTEAPATDIAATETTPAPSVP 378

  Fly   380 EGIEDGLTAAMD--NLVPEELAEASDKQETELESEDQQSPVTEAIEEQAVPEIEQEKEKEPEQIT 442
            ..:.|. .|..|  :.:|||....:        :||..:|.:.|.||...|....|:...||..:
Worm   379 APVADA-AAGYDSPSSIPEETPAPA--------AEDTPAPASAAAEETPAPAPAAEETPAPETAS 434

  Fly   443 LADETEQDSAQPSNEEPVEI---APEQHTEAEIAPAKIPEEGKPEEEVQVEEESKPVEESKPEE- 503
            .|.:....:|......|.::   |||. :.|:.|........:|..||     :.|:.||..|.
Worm   435 AAPDAAGGAAPADVAAPADVATTAPET-SSAQSAAGSYDVPSEPASEV-----TAPIVESATEAP 493

  Fly   504 -------------------EIKQQEDAKPEEDDQNYAETQPAVTEVKPEETPADIPVEIPAEVPA 549
                               |....:.|..|......||..||.......:.|:.:|.|.||..||
Worm   494 SDSAAPIGPAASEPAPAPIEAPATDAATLETAPAPAAEPAPAAEAAAGYDAPSSVPEETPAPAPA 558

  Fly   550 --EIPAEIPA--EVPAEIPA----ESPAEIAAEVPAEIPA--EIPAEIPA--ETPA------ETH 596
              |.||..||  |.||..||    .:||..|.|.||..||  |.||..||  ||||      ||.
Worm   559 ADETPAPAPAAEETPAPAPAAEETPAPAPAAEETPATAPAAEETPAPAPAADETPAPAPAAEETP 623

  Fly   597 AEIPA----DVPAQVVAEAPAETPA--ETPAEVP--AEIPSKVQDEIQSDSTQAEPQVEKEAQQP 653
            |..||    ..||..|.|.||..||  ||||..|  ||..:.|.:|..:.:..|| :....||..
Worm   624 APAPAVEETPAPAPAVEETPAPAPAAEETPAPAPAAAEYAAPVAEETPAPAPAAE-ETPAPAQAA 687

  Fly   654 EKETKPLESSLLTTIIPMVMPQPQVPSQPLQVQDSVLNYVNASFMQQQPS------ETDLPKTE- 711
            |:...|..::..|   |...|..:....|            |...::.|:      ||..|..|
Worm   688 EETPAPAPAAEET---PASAPAAEETPAP------------APAAEEAPAPAPAAPETPAPAAEG 737

  Fly   712 EESPFNAHLRRYDGAQVWRIVVQTDKDKRMADEL-QSKYDGQLWKEVKQEVDYLLKPQVLAAAER 775
            ..:|.......||.||....||.:......:|.. .:.|:||.:              .:.||.:
Worm   738 AAAPAPIVSSGYDAAQSTDTVVASSAPATSSDASGATNYEGQQF--------------AIQAARK 788

  Fly   776 HIRAA 780
            .:|.|
Worm   789 KVRRA 793

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	9/51 (18%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844
ZK84.1	NP_495202.1	DUF935	<555..615	CDD:303044	28/59 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910