DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and ZC434.9

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	NP_001251356.1	Gene:	ZC434.9 / 172908	WormBaseID:	WBGene00013895	Length:	720	Species:	Caenorhabditis elegans

Alignment Length:	410	Identity:	133/410 - (32%)
Similarity:	215/410 - (52%)	Gaps:	43/410 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   746 QSKYDGQLWK---EVKQEVDYLLKPQVLAAAERHIRAANLSRIVLIDNLQR-VIEKENPPAEKIA 806
            ::::|...|:   :|....|.::....:...:..::.:|:|..|:|:::.: ::|||:.|.....
Worm    55 RTQHDLDFWQTPSKVGHRADIMVDEDRMEWLDSVLKNSNISYDVIIEDVGKLILEKEHGPPRFSN 119

  Fly   807 ELQNRKGH-------RLTWQAYHRLEDIHGFIDYMAKTYPDICSTEIIGYSVEKRPLKILKISNG 864
            .|.:::.|       |..:..||..:.|..::..:.:.|||......:|.:.|.||::.:||.:.
Worm   120 LLFSKRMHNEGGNRARYGFGEYHSYQTICDWMKDIERKYPDKAKVFTMGTTSEGRPIQGIKIGSQ 184

  Fly   865 NARNPG--IWIDGGMHAREWISPATVTYIANQLVEGWED---LPEHMRSINWYIHPVANPDGYEY 924
            ..||..  .|||||:|||||.:..|..:..::|:..:.|   :...:..:|:||.||||||||||
Worm   185 VWRNDKRIFWIDGGIHAREWAAVHTALWFIDRLIADYNDDSLVRAAVDRLNFYILPVANPDGYEY 249

  Fly   925 SHT----TDRLWRKNMRA----------HGRQCPGVDLNRNFGYKWGGKGTSASPCSQTYRGSKA 975
            |.:    ..|||||| ||          ..|.|.|||||||:.:.:|..|:|...||:.|:||.|
Worm   250 SRSDVSPMIRLWRKN-RAGVVCKKDRWFRDRCCGGVDLNRNYDWHFGETGSSTDKCSEIYQGSSA 313

  Fly   976 FSEPET-----FYISKFISGFPRETFQAYLSFHSYGQYILYPWGYDYQ-LTQDRADLDRVARQAG 1034
            |||.||     |..|..::|    ...|:::.|:|.|..::|:.:..: :..|.|:|.||.|.|.
Worm   314 FSESETRSMRDFLTSSELNG----KIDAFITLHTYSQMWIHPYSHARKSVPADVAELQRVGRAAV 374

  Fly  1035 TSITKSTGVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIEM--GDTGRYGFVLPARFIQYN 1097
            .::..:.|.||..|:.:..|||:||||||||||...|||.|.:|:  |:....||:|....:...
Worm   375 AALENTYGTKYKFGTGSDILYPSAGGSDDWAKGTLRIKYVYLLELRPGEDVWDGFILDQHQLIPT 439

  Fly  1098 GKDGVTFADTVARAIAQGRG 1117
            .|:.......|.||:.:..|
Worm   440 AKETWNGIKVVIRAVTEQAG 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	8/54 (15%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	116/317 (37%)
ZC434.9	NP_001251356.1	Propep_M14	45..111	CDD:366995	9/55 (16%)
		M14_CP_A-B_like	141..454	CDD:349433	116/317 (37%)
		ShK	682..719	CDD:366702
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8411
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.920