DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and suro-1

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	NP_492177.2	Gene:	suro-1 / 172557	WormBaseID:	WBGene00011235	Length:	664	Species:	Caenorhabditis elegans

Alignment Length:	487	Identity:	145/487 - (29%)
Similarity:	229/487 - (47%)	Gaps:	86/487 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   705 TDLPKTEEESPFNAHLRRYDGAQVWRIVVQTDKDKRMADELQ---SKYDGQLWK---EVKQEVDY 763
            ||:..|:::... .|:..:|           ::...:..:||   .|||...||   .:..:.|.
Worm    25 TDVHNTDDKYAL-IHVSAHD-----------EQSLHLIKQLQLNDFKYDLDFWKSPSSISDKADI 77

  Fly   764 LLKPQVLAAAERHIRA----ANLSRIVLIDNLQRVIEK--------------------ENPPAEK 804
            ::|   ...:||.:|.    ||::..:.:.:::::|.:                    ::|..:.
Worm    78 MVK---RGKSERMLRQILSFANVTVSMSVPDVEKLIMRNEGTTSKSHLGFGSLSKWLHDDPILDS 139

  Fly   805 IAELQNRKGHRLTWQAYHRLEDIHGFID---YMAKT---YPDICSTEIIGYSVEKRPLKILKI-S 862
            ..:|...|...|. :|.:...|...:.|   ||...   ||.|.....||.:.|.:|::.||| :
Worm   140 EPDLDLTKVGALK-KAKYPFGDYASYADMVKYMRTIEFYYPRIAKIVRIGATHEGKPIEGLKIGA 203

  Fly   863 NGNARNPGIWIDGGMHAREWISPATVTYIANQLVEGW---EDLPEHMRSINWYIHPVANPDGYEY 924
            ..:.:...:|:||.:|||||.|..|..|..||||..:   ..:..::.::::||.|..|||||||
Worm   204 RSSHKKRAVWVDGNIHAREWASSHTALYFINQLVSEYGKDAQITNYVDTLDFYIVPCLNPDGYEY 268

  Fly   925 SHT----TDRLWRKNMRAH--------GRQ-CPGVDLNRNFGYKWGGKGTSASPCSQTYRGSKAF 976
            :.|    |.||||||....        |.: |.||||||||.:.|..:|:|..|||..|.|.:.|
Worm   269 TRTSPIPTVRLWRKNRSPELCRPSLWGGEKCCRGVDLNRNFRFHWAERGSSYEPCSNIYHGEEVF 333

  Fly   977 SEPETFYISKFISGFP--RETFQAYLSFHSYGQYILYPWGYDYQ-LTQDRADLDRVARQAGTSIT 1038
            |||||..:..|:: .|  ::...|:::.|||.|..:||:.::.| ..:|..:|.:.||:|...::
Worm   334 SEPETRAVRNFLA-TPEMKDRVDAFVTLHSYAQLWIYPYSHEEQNYPEDIGELRKTARKAINRLS 397

  Fly  1039 KSTGVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIEMGDTGRY--GFVL------PARFIQ 1095
            :..|..|.:|:.|.||.|||||||||||....:||.|.||:......  ||:|      |.....
Worm   398 RVYGTNYRMGTGADTLSPAAGGSDDWAKSALNVKYVYLIELRPQMELSNGFILHKKELIPTAVET 462

  Fly  1096 YNGKDGVTFADTVARAIAQGRGKSVARNSSGS 1127
            :.|     |.:.|...:......|....||||
Worm   463 FEG-----FREVVDAVLTLNNSTSSIGLSSGS 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	15/76 (20%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	115/324 (35%)
suro-1	NP_492177.2	Propep_M14	39..110	CDD:280416	15/84 (18%)
		M14_CP_A-B_like	161..473	CDD:199844	114/317 (36%)
		ShK	620..657	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8411
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.820