DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and T06A4.1

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	NP_871809.1	Gene:	T06A4.1 / 171669	WormBaseID:	WBGene00020281	Length:	606	Species:	Caenorhabditis elegans

Alignment Length:	431	Identity:	156/431 - (36%)
Similarity:	221/431 - (51%)	Gaps:	60/431 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   723 YDGAQVWRIVVQTD---KDKRMADELQSKYDGQLWK---EVKQEVDYLLKPQVLAAAERHIRAAN 781
            |...::.||..:|:   |..|...|..|.|:...|:   .:...||..:.|.......:.:.:..
Worm    29 YHNFKLIRINPETEGSVKYLRSLYEDPSPYELDFWQPPTNIGAIVDLTVAPADAPRFVKDLESKK 93

  Fly   782 LSRIVLIDNLQRVIEKE-------NPPAEKIAELQNRKGHRLTWQAYHRLEDIHGFIDYMAKTYP 839
            :|.||.:::|.:.||.|       ||.|            ...:..|:.||:|...:..:.|.||
Worm    94 ISYIVAVNDLSKAIENERGSDKFYNPVA------------GFAYDKYNSLEEIQTEMKRLKKEYP 146

  Fly   840 DICSTEIIGYSVEKRPLKILKISNGNARNP-----GIWIDGGMHAREWISPATVTYIANQLVEGW 899
            .:.:...||.|.|.|.|.::||:  ..|||     .:|||.|:||||||:|||..|||::|:.|:
Worm   147 TMITLIDIGQSHENRTLLVMKIT--GKRNPLGSKISMWIDAGIHAREWIAPATAMYIAHELLLGY 209

  Fly   900 ED---LPEHMRSINWYIHPVANPDGYEYSHTTDRLWRKNMRAH--GRQ------CPGVDLNRNFG 953
            |:   :.:.|..|::||.||.||||||||...:|:||||....  .||      |.||||||||.
Worm   210 ENDATVAKLMDHIDFYILPVMNPDGYEYSREKNRMWRKNRSPAKCARQTFSTVCCSGVDLNRNFD 274

  Fly   954 YKWGGKGTSASPCSQTYRGSKAFSEPETFYISKFISGFPRETFQAYLSFHSYGQYILYPWGYDYQ 1018
            :.|...|:|:.||..||.||.||||||:..:..|:.   :.|.:|::|.|||.|..|.|:|:..|
Worm   275 WFWASTGSSSDPCHDTYHGSAAFSEPESQAVRDFLE---QNTPEAFISLHSYSQMWLIPYGHRKQ 336

  Fly  1019 -LTQD-RADLDRVARQAGTSITKSTGVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIE--- 1078
             ..|| ...|..:|.:|..::.:..|.||.||:.|..:|.|:|||.|||||...:.|||.||
Worm   337 SYPQDYHTGLRPLALRATKALYELYGTKYQVGTGADLMYEASGGSHDWAKGQLKVPYAYLIELRP 401

  Fly  1079 ----MGDTGRYGFVLPARFIQYNGKDGVTFADTVA-RAIAQ 1114
                ||    :||:||.|.|...|.:.......|| ..:||
Worm   402 KNTMMG----HGFLLPEREIVPTGLETFESIKVVADELVAQ 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	17/72 (24%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	131/316 (41%)
T06A4.1	NP_871809.1	Propep_M14	40..110	CDD:366995	16/69 (23%)
		M14_CP_A-B_like	128..435	CDD:349433	131/315 (42%)
		ShK	568..602	CDD:366702
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8411
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.950