DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and T06A4.3

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	NP_001021611.1	Gene:	T06A4.3 / 171668	WormBaseID:	WBGene00020283	Length:	505	Species:	Caenorhabditis elegans

Alignment Length:	466	Identity:	142/466 - (30%)
Similarity:	216/466 - (46%)	Gaps:	80/466 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   707 LPKTEEESPFNAHLRRYDGA-----QVWRIVVQTDKDKR-----MADELQSKYDGQLWKEVKQEV 761
            |||::.:  |.|..|.|..|     ..|:    |.|||.     |.|...|||          .:
Worm    29 LPKSQTD--FQAIQRLYKNATDHDLNFWK----TGKDKHGFWDVMVDMKNSKY----------FL 77

  Fly   762 DYLLKPQVLAAAERHIRAANLSRIVLIDNLQRVIEKENPPAEKIAELQN---------RKGHR-- 815
            |:|             :..::|.|..||:::.:|.|.    |....|.|         ...|.
Worm    78 DFL-------------QVNDISYIKTIDDVEGLITKH----ENNKTLSNMFPRLWDDSSSAHYDF 125

  Fly   816 LTWQAYHRLEDIHGFIDYMAKTYPDICSTEIIGYSVEKRPLKILKISNGNARNPGI-WIDGGMHA 879
            .|:.:|.|:.|   ::..:...||.:.....||.:.|.|.:..::| .|::|...| |||||:||
Worm   126 HTYGSYQRMTD---WMKQLVVKYPKMVQYISIGKTTEGRNIDGVEI-GGDSRTKKIFWIDGGIHA 186

  Fly   880 REWISPATVTYIANQLVEGWED--LPEHMRSINWYIHPVANPDGYEYSHTTD----RLWRKN--- 935
            |||.:|.|..:..:||.....:  :.:.:..|.:.:.|..||||||::.::.    ||||||
Worm   187 REWAAPHTALFFIHQLTSRANEPGIKKLLNEITFVVVPCLNPDGYEFTRSSTNPHVRLWRKNRSK 251

  Fly   936 ------MRAHGRQCPGVDLNRNFGYKWGGKGTSASPCSQTYRGSKAFSEPETFYI-SKFISGFPR 993
                  :....|.|.||||||||.:.:...|||..|||:.|:|...|||||...: ...:|...:
Worm   252 MQCRKDIWGRNRCCRGVDLNRNFDFHFRESGTSDDPCSEIYQGPSPFSEPEAKAVRDALLSQRYK 316

  Fly   994 ETFQAYLSFHSYGQYILYPWGYDYQ-LTQDRADLDRVARQAGTSITKSTGVKYTVGSSATTLYPA 1057
            ....||::.|:|.|..::|:|:... ...|..||..|.::|..::.:..|.||.|||.|.|||||
Worm   317 GRTDAYITLHTYSQIWIHPYGHKKDAYPGDIKDLYEVGKKAAQALKRVYGTKYVVGSGADTLYPA 381

  Fly  1058 AGGSDDWAKGIAGIKYAYTIEM--GDTGRYGFVLPARFIQYNGKDGVTFADTVARAIAQG--RGK 1118
            :|||:||||..|.:|:.|.:|:  .:....||:|..:.:....::.......||.|:...  .||
Worm   382 SGGSEDWAKHEAKVKFVYLLELRPDEKNWDGFILDEKELIPTARETWEGVRVVAEAVLDRIVAGK 446

  Fly  1119 SVARNSSGSRR 1129
            |.|...:...|
Worm   447 STAPREAPKAR 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	16/71 (23%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	105/310 (34%)
T06A4.3	NP_001021611.1	Propep_M14	31..98	CDD:366995	22/95 (23%)
		M14_CP_A-B_like	128..438	CDD:349433	105/313 (34%)
		ShK	468..505	CDD:366702
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8411
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.920