DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and CBPA1_ANOGA

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	XP_318615.2	Gene:	CBPA1_ANOGA / 1278958	VectorBaseID:	AGAP009593	Length:	433	Species:	Anopheles gambiae

Alignment Length:	396	Identity:	142/396 - (35%)
Similarity:	218/396 - (55%)	Gaps:	26/396 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   718 AHLRRYDGAQVWRIVVQTDKDKRMADELQSKYDGQLWKEVKQEV----DYLLKPQVLAAAERHIR 778
            |.:.|||..:::|:...::...|....::...|..::.|..:::    |.::.|..||.....:.
Mosquito    29 AEVARYDNYRLYRVTPHSEAQLRSVAAMEQASDSLIFLETARKLGDRFDIVVAPHKLADFTETLE 93

  Fly   779 AANLSRIVLIDNLQRVIEKENPPAEKIAELQNRKGH-RLTWQAYHRLEDIHGFIDYMAKTYPDIC 842
            :..:...::..|:||..::|.      ..|.|::.. ...|..||.||:||.::|.:|..:|...
Mosquito    94 SDYIPHELIEQNVQRAFDEER------VRLTNKRAKGPFDWNDYHTLEEIHAWLDQLASEHPKEV 152

  Fly   843 STEIIGYSVEKRPLKILKISNGNARNPGIWIDGGMHAREWISPATVTYIANQLVEGWED-----L 902
            .....|.|.:.|.:|.:|:|.|..| ||::::||:||||||||||||||.|||:.. ||     |
Mosquito   153 ELLDAGRSHQNRTMKGVKLSYGPGR-PGVFLEGGIHAREWISPATVTYILNQLLTS-EDAKVRAL 215

  Fly   903 PEHMRSINWYIHPVANPDGYEYSHTTDRLWRKNMRAHGRQCPGVDLNRNFGYKWGGKGTSASPCS 967
            .|   ..:||:.|.||||||.|:...:|||||..:|:|..|.|.|.|||:.:.|..:|||.:.||
Mosquito   216 AE---KFDWYVFPNANPDGYAYTFQVNRLWRKTRKAYGPFCYGADPNRNWDFHWAEQGTSNNACS 277

  Fly   968 QTYRGSKAFSEPETFYISKFISGFPRETFQAYLSFHSYGQYILYPWGYDYQLTQDRADLDRVARQ 1032
            .||.||:||||.||..::.|:... |....||::||||.|.:|:|:|:..:.:.:..||:.:|..
Mosquito   278 DTYHGSEAFSEVETRSLAAFVEKL-RGKLGAYIAFHSYSQLLLFPYGHTGEHSPNHQDLNEIAEA 341

  Fly  1033 AGTSITKSTGVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIEM---GDTGRYGFVLPARFI 1094
            ...|:.|..|.:|..|:....:|||:|.|.||:.|...:|.|||.|:   ||... |||||...|
Mosquito   342 TVKSLAKRYGTQYKYGNVYDAIYPASGSSVDWSYGAQDVKIAYTYELRPDGDAWN-GFVLPPNEI 405

  Fly  1095 QYNGKD 1100
            ...|::
Mosquito   406 VPTGEE 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	11/70 (16%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	123/288 (43%)
CBPA1_ANOGA	XP_318615.2	Propep_M14	41..112	CDD:280416	11/70 (16%)
		MpaA	74..410	CDD:225421	133/348 (38%)
		M14_CP_A-B_like	131..422	CDD:199844	123/288 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X86
TreeFam	0	0.000	Not matched by this tool.
	5	4.820