DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and AgaP_AGAP012947

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	XP_003436089.1	Gene:	AgaP_AGAP012947 / 11175807	VectorBaseID:	AGAP012947	Length:	472	Species:	Anopheles gambiae

Alignment Length:	444	Identity:	80/444 - (18%)
Similarity:	141/444 - (31%)	Gaps:	90/444 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   271 AQPEAEPQLEVEPQPEVESQPEVESQPEVEAQPEVEPQSEVESQPEAESHSEPETQAEVEAQPEV 335
            |:|::.|......:|:....||.:...:.|.|.:.:.|.:.:.|.|:..::|....|....|...
Mosquito    73 ARPQSAPNKHYHYRPQYRPAPEPDQYDDNEEQDQQDQQDQEQQQQESSDYAEDSATAGATHQYMT 137

  Fly   336 ESLPEAESQPEAESQPEREPEVEAEKISDNEVDTTEASLMETLVEGIEDGLTAAMDNLVPEELAE 400
            ......:.......:|...   ::|:..|.:...:|.|.........:               .:
Mosquito   138 TYKTSTKHGGGTRYRPSYS---DSEEEDDEDTCASEESNAYNAYRAYQ---------------GK 184

  Fly   401 ASDKQETELESEDQQSPVTEA-------IEEQAVPEIEQEKEKEPEQITLADETEQDSAQPSNEE 458
            .|.|.:|...|....|....:       ::.|..|:.:::.:::.:|.......:|...|.|...
Mosquito   185 GSKKPQTHHASSSAASSGLGSNRYHQHYVQHQHRPKHQEQHQQQQQQHHHHHHRQQQQQQSSYHH 249

  Fly   459 PVEIAPEQHT--EAEIAPAKIPEEGKPEEEVQVEEESKPVEESKPEEEIKQQEDAKPEED----- 516
              ...|..||  ..::..|.....|.|.:        .|......::|...:|..:.:||
Mosquito   250 --HHVPSAHTSYHPQLIQAYKILHGTPNQ--------LPTSHEYTDDEDGSEEFDEEDEDFHSGA 304

  Fly   517 --------DQNYAETQPAVTEV---KPEETPADIPVEIPAEVPAEIPAEIPAEVPAEIPAESPAE 570
                    ...|..|..|..::   |....|....|||...||.....:|...:|.|:..:.|..
Mosquito   305 AIGAAAGLTSGYGATGSAAHQIIHTKGRAVPISQHVEIETPVPVPYVKKIHVPIPQEVRIKIPHP 369

  Fly   571 IAAEVPAEIPAEIPAEIPAETPAETHAEIPAD----VPAQVVAEAPAETPAETPAE--VPAEIPS 629
            :...||...|..||...|...|......:|.:    .|.:.....|.|.|...|.|  ||..:|.
Mosquito   370 VLVPVPRPYPVHIPVAQPIAVPDIKEITVPIEKIVPYPVEKKIPVPIEKPVPYPVEKHVPVYLPH 434

  Fly   630 KVQDEIQSDSTQAEPQVEKEAQQPEKETKPLESSLLTTIIPMVMPQ----PQVP 679
            .:                           |::..::.|||..|..|    |.:|
Mosquito   435 PI---------------------------PVKVPIVKTIIHKVKQQTASGPPLP 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844
AgaP_AGAP012947	XP_003436089.1	predic_Ig_block	371..>456	CDD:275319	23/111 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910