DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and cpz

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	XP_012812537.1	Gene:	cpz / 100170588	XenbaseID:	XB-GENE-994183	Length:	662	Species:	Xenopus tropicalis

Alignment Length:	484	Identity:	93/484 - (19%)
Similarity:	159/484 - (32%)	Gaps:	143/484 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   687 DSVLNYVNASFMQQQPSETDLPKTEEESPFNAHLRRYDGAQVWRIVVQTDKDKRMADELQSKY-- 749
            |::|.|.|           |||.::...| ||                .|:..|...|..::|
Frog    49 DNILGYCN-----------DLPYSKTMFP-NA----------------LDQQSRGEIEFSAEYIL 85

  Fly   750 ----DGQLWKEVKQEVDYLLKPQVLAAAERHIRAANLSRIVLIDNLQRVIE--KEN--------- 799
                |..|..|...::      :::..|   :.|....:..::...:||.|  |:|
Frog    86 LSVIDNLLQGECNPDL------RIVGCA---VLAPRCEKNKMVKPCRRVCETLKKNCLPAFDAID 141

  Fly   800 ---------------------PPAEKI-AELQNRKGHRLTWQAYHRLEDIHGFIDYMAKTYPDI- 841
                                 .|.||: ..::......||       |....||.::..:|.|:
Frog   142 MAWPYFLDCERFFVGEEEGCHDPLEKLRVNIEITPEDLLT-------ETPSTFIQFIHHSYSDMV 199

  Fly   842 ---------CS----TEIIGYSVEKRPLKILKIS----NGNARNPGIWIDGGMHAREWISPATVT 889
                     ||    |..||.|.|.:.|..::.|    ...|..|.....|.||..|......:.
Frog   200 RVLKKTAARCSQISKTYSIGRSYEGKDLLAIEFSAQPGQHKALTPEFRYIGNMHGNEVAGRELLI 264

  Fly   890 YIA----NQLVEGWEDLPEHMRSINWYIHPVANPDGYEYSHTTDRLWRKNMRAHGR-QCPGVDLN 949
            |:|    ::.:.|...:...:.:...::.|..||||||  |..:.....|...:|| ....:|||
Frog   265 YLAQFLCSEYLLGNSRIQTLINTTRIHLLPSMNPDGYE--HAAEEGAGYNGWTNGRLNAQNIDLN 327

  Fly   950 RNFG---------YKWGGKGTSASPCSQTYRGSKAFSEPETFYISKFISGFPRETFQAYLSFHSY 1005
            |||.         .:.........|..::|...|.  .||...:.|::...|   |....|.|..
Frog   328 RNFPDLTSEVHKIIRMPMARLDHMPIPESYWDGKI--APEAKAVMKWMRSIP---FVISGSLHGG 387

  Fly  1006 GQYILYPWGYDYQLTQDRADLDRVARQAGTSITKSTGVKYTVGSSATTLYPAAGGS--------- 1061
            ...:.||:.:.....:::........:....:.|:....:.:.|..:|  ...||:
Frog   388 DLVVSYPYDFSRHPLEEKMFSPTPDEKVFQMLVKTYVAAHPIMSDKST--SRCGGNFNNKGGIIN 450

  Fly  1062 -DDW---AKGIAGIKYAY------TIEMG 1080
             .:|   :.|:|...|.:      |:|:|
Frog   451 GAEWYSFSGGMADFSYLHTNCFELTLELG 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	12/74 (16%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	64/311 (21%)
cpz	XP_012812537.1	CRD_FZ	46..169	CDD:382974	27/156 (17%)
		M14_CPZ	192..506	CDD:349439	61/297 (21%)
		Peptidase_M14NE-CP-C_like	510..586	CDD:200604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910