DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3108 and cpo.1

DIOPT Version :9

Sequence 1:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster
Sequence 2:	XP_031748368.1	Gene:	cpo.1 / 100145253	XenbaseID:	XB-GENE-989447	Length:	451	Species:	Xenopus tropicalis

Alignment Length:	400	Identity:	127/400 - (31%)
Similarity:	211/400 - (52%)	Gaps:	36/400 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   718 AHLR-RYDGAQVWRIVVQTDKDKRMADELQSKYDGQLWKEVKQEVDYLLKPQVLAAAERHIR--- 778
            |:|: :|:|.||.::.::|..|......:..:....|||..:.|       .:....|.|:|
Frog    19 AYLKVQYNGDQVLKLTLKTTDDCEHMQNICKQLQLDLWKPSRIE-------DIQPGKEMHVRIPF 76

  Fly   779 ------AANLSRI-----VLIDNLQRVIEKENPPAEKIAELQNRKG--HRLTWQAYHRLEDIHGF 830
                  ..||.:.     |:|.::|::|:..|     :.:.:.:|.  ....:..||.:::|:.:
Frog    77 PLLQKFKENLHQYSIPFEVMIKDVQKLIDSSN-----VGDYRRQKKILAEFDYTTYHPMDEIYQW 136

  Fly   831 IDYMAKTYPDICSTEIIGYSVEKRPLKILKIS-NGNARNPGIWIDGGMHAREWISPATVTYIANQ 894
            :|.:.:.|.|:.|...:|.:.|.||:...||. ..:.:...||:|.|:||||||:.|...:...:
Frog   137 MDQVKEAYSDLVSMHYLGSTYELRPIYYFKIGWPSDKQKKIIWMDCGIHAREWIAVAYCQWFVKE 201

  Fly   895 LVEGWEDLP---EHMRSINWYIHPVANPDGYEYSHTTDRLWRKNMRAHGR-QCPGVDLNRNFGYK 955
            ::|..:..|   :.:.:|::||.||.|.||:.||...:|||||:...|.. .|.||||||||..|
Frog   202 ILETHKTNPLLQKVLHNIDFYIVPVLNIDGFVYSWNVNRLWRKSRSPHNNGSCYGVDLNRNFNSK 266

  Fly   956 WGGKGTSASPCSQTYRGSKAFSEPETFYISKFISGFPRETFQAYLSFHSYGQYILYPWGYDYQLT 1020
            ||..|.|.:...:||.|:...||||...:||.:.....:.. .:|:.|||||.:|.|:||....:
Frog   267 WGSIGASNNCRDETYCGTGPASEPEVNAVSKLLGSLKSDVL-CFLTIHSYGQLLLLPYGYTKDPS 330

  Fly  1021 QDRADLDRVARQAGTSITKSTGVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIEMGDTGRY 1085
            .:..::..||::|...:.:..|.:|.|||::..||..:|.|.|||..: ||.::||.|:.|||.:
Frog   331 INHEEMINVAQKAAAKLQEKHGTEYRVGSTSHLLYSNSGSSRDWATDL-GINFSYTFELRDTGAH 394

  Fly  1086 GFVLPARFIQ 1095
            ||:|||..|:
Frog   395 GFILPANQIR 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	15/80 (19%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	104/279 (37%)
cpo.1	XP_031748368.1	Propep_M14	36..105	CDD:396700	14/75 (19%)
cpo.1	XP_031748368.1	M14_CPO	124..421	CDD:349466	104/282 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm9338
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.950