DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42264 and CG18585

DIOPT Version :9

Sequence 1:	NP_572260.2	Gene:	CG42264 / 31504	FlyBaseID:	FBgn0259149	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_001260213.1	Gene:	CG18585 / 34041	FlyBaseID:	FBgn0031929	Length:	422	Species:	Drosophila melanogaster

Alignment Length:	442	Identity:	110/442 - (24%)
Similarity:	203/442 - (45%)	Gaps:	77/442 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 SPGSSYQINRRY--------------RNGSQVQRYYGFQLWKVHETRLEQPELRAFWRHFGSEVW 250
            ||...|...|.|              :.|...::|   .:||.::.|..|
  Fly    22 SPKERYDNFRVYKLTIQNKIQLAAIEKIGELTKKY---NIWKEYDERSRQ--------------- 68

  Fly   251 NINQDGIDILIEQRNVADARKFMDKVGYSYNIMIDDIESAIDESYVEVPAVEHPLDSVRNNSLPW 315
                  |||::....:...::.:.....|..:||::::..|||..|...|     ||
  Fly    69 ------IDIMVSPGELNHFQELLKFNNISSELMIENVQERIDEEQVTPTA-----DS-------- 114

  Fly   316 MEVPGSTMNWRRYHDQADIKQFLQTLLETYSENVELIQIGVTRNKRPLEVIRVSN--GNPDNWAV 378
                 :|..|.:|::..:|:.:|..:|..|....|...:|.:...|.:..|::|:  |||   .:
  Fly   115 -----ATFGWTKYYELEEIEAWLDEILNAYPSVTEEFIVGKSYEGRTIRGIKISHKAGNP---GI 171

  Fly   379 FVDAGLQARDWLSPAALTYAISKLTHLWGRPKGKDKGEGQRQSRAEKAMRRIDWYFLPLANPDGY 443
            |:::.:.||:|::.|:.|:.|::|.         ...:...:|.|:    ..||:.:|:.|.||:
  Fly   172 FIESNIHAREWITSASATWFINQLL---------TSEDADVRSLAD----NYDWHIIPVFNVDGF 223

  Fly   444 QYSRQTDRLWTKNRGYDSVSGCYGVNLDRNFDYGW-DGTGSTSNPCKNLYRGAHSFSEPESRAVC 507
            :||.:.||:|.|.|...:.:.|.|.:.:||||..| ...|::.|||...:.|.:..||||::|:.
  Fly   224 EYSHKKDRMWRKTRQPHATNACIGADANRNFDSYWLQNNGASDNPCSETFAGDNPESEPEAKALV 288

  Fly   508 SFLSGMREYLGAYVSLGGYGQAITYPWGDA-DYVTENQRNLKQTARRAVLALRRLNQAE-YSSGT 570
            .:|:.:::.:..|:|...|||.:..|:|.. :...||..::....:....|:..|.... |..|:
  Fly   289 EYLTKIQDQISVYISFHSYGQYLLSPYGHTNEEFPENYNDILTIGKAFADAIEALPYGTVYQYGS 353

  Fly   571 SYRQKLARPGNSADWVQDRIGPQLVFNMFLKDQGRYGYLLPPHYIVESGEEV 622
            :........|.|.|||.:.:|.::.:.:..:|:||||::|||..|:.:.||:
  Fly   354 TADVLYVATGTSVDWVFNELGKKIGYTIEYRDKGRYGFILPPVQIIPNCEEL 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42264	NP_572260.2	Propep_M14	<241..293	CDD:280416	7/51 (14%)
CG42264	NP_572260.2	M14_CP_A-B_like	328..633	CDD:199844	84/300 (28%)
CG18585	NP_001260213.1	Propep_M14	34..105	CDD:280416	13/94 (14%)
CG18585	NP_001260213.1	M14_CP_A-B_like	122..415	CDD:199844	84/300 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467032
Domainoid	1	1.000	166	1.000	Domainoid score	I805
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I1180
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
	9	8.900