DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42264 and W01A8.6

DIOPT Version :9

Sequence 1:	NP_572260.2	Gene:	CG42264 / 31504	FlyBaseID:	FBgn0259149	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_492003.2	Gene:	W01A8.6 / 189076	WormBaseID:	WBGene00012168	Length:	380	Species:	Caenorhabditis elegans

Alignment Length:	331	Identity:	90/331 - (27%)
Similarity:	155/331 - (46%)	Gaps:	39/331 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   328 YHDQADIKQFLQTLLETYSENVELIQIGVTRNKRPLEVIRVSNGNP-----DNWAVFVDAGLQAR 387
            |:|....:.:::.:.......|:|..||.||..|||..:|:  |.|     ...||::|.|..||
Worm    35 YNDWPQFEDYIKGVAHDNPSFVQLKTIGRTREGRPLLGVRI--GKPALPGKRKIAVWLDGGNHAR 97

  Fly   388 DWLSPAALTYAISKLTHLWGRPKGKDKGEGQRQSRAEKAMRRIDWYFLPLANPDGYQYSRQTDRL 452
            :|.:.....|.|.||.:.:           ....:..|.:..:|.|..|:.||||:.|||.:.|.
Worm    98 EWPAFHVAVYFIEKLVNGY-----------LSDDKITKYVETLDIYVFPVLNPDGFVYSRTSTRA 151

  Fly   453 ----WTKNRGYDSVSG---------CYGVNLDRNFDYGWDGTG-STSNPCKNLYRGAHSFSEPES 503
                |.|||..::.:|         |.||:|:||:|.|:.... ..:|||.:.::|...|||||:
Worm   152 MIRQWRKNRAPENCTGTGPFQTDICCEGVDLNRNYDIGFSHKNYPFNNPCSDEFQGPRPFSEPET 216

  Fly   504 RAVCSFLSGMREY--LGAYVSLGGYGQ--AITYPWGDADYVTENQRNLKQTARRAVLALRRLNQA 564
            |||..|:.....|  |.|.||:..:||  .:.|.:....| .::.::|:..|.||...:....:.
Worm   217 RAVRDFIMSSEIYGRLYALVSMHTHGQLWILPYNYQKRTY-PQDIKDLEILANRAADRVFAYRET 280

  Fly   565 EYSSGTSYRQKLARPGNSADWVQDRIGPQLVFNMFLKDQGR--YGYLLPPHYIVESGEEVFEFLR 627
            :|..||:........|.:.||::.....:.|:.:.|....:  :.:.:.||:::..|:|.:..:.
Worm   281 KYRVGTAADMLGTATGGATDWIKKNTPTKYVYVLELPPDMKTWFAFQVKPHWLIPIGKETWLGIE 345

  Fly   628 IIAQQL 633
            :|..|:
Worm   346 VIFDQV 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42264	NP_572260.2	Propep_M14	<241..293	CDD:280416
CG42264	NP_572260.2	M14_CP_A-B_like	328..633	CDD:199844	89/329 (27%)
W01A8.6	NP_492003.2	Zn_pept	35..337	CDD:214748	86/315 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920