Protein Alignment CG42264 and ccpp-1

DIOPT Version :10

• Sequence 1: NP_572260.2
• Gene: CG42264 / 31504
• FlyBaseID: FBgn0259149
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_491674.2
• Gene: ccpp-1 / 172241
• WormBaseID: WBGene00018995
• Length: 1015
• Species: Caenorhabditis elegans
• Alignment Length: 735
• Identity: 131/735 - (17%)
• Similarity: 230/735 - (31%)
• Gaps: 269/735 - (36%)

  Fly    58 PLSMSPPSERGKISELRSELDANYVSYRGAQLWKLNFNATRGS---SMAE------REEDDEAAE 113
            ||..:.||..|....:|:....|           ::|:..|.|   .|.|      |::|||..:
 Worm   383 PLPTATPSTPGGHGRIRNSSSIN-----------ISFDNGRSSDEDGMDEEDEAFVRDDDDEGKD 436

  Fly   114 KR---QVLASPDAQFN-----------EVVALFALTFV--------ALIGSVFGQKLLLWRSV-- 154
            .|   ......|.:.|           :.:|.:|..||        .....::......|||:
 Worm   437 DRGSDDDDGKDDDEINGALPKTTRLNPQQLAKYAPFFVENEQGTLQPTFSMIYQTNQESWRSICE 501

  Fly   155 SVPEISGI-SGLPLALLTL----------NSSELYESTLEGL----------QWLSPMDLRRFD- 197
            ....:..| ..||:.:...          .|:.:.:..:|.|          |.:..:|...||
 Worm   502 KTRHVMPIHHHLPIEMFNTPTRIREKTAKTSNNMKKMIIEELDKPERSATSNQVIYDLDTAAFDG 566

  Fly   198 -------FISPG------SSYQINRRYRNG---------------------SQVQRYYGFQLWKV 228
                   |::.|      ...|.:.|:.:|                     :|::.:|.:..::|
 Worm   567 LPSPELPFVTGGGKLDTSKDLQFDSRFESGNLRMVIQVAPTHYELFLSPDVNQLRDHYQWFFFQV 631

  Fly   229 HETRLE---------------------QPELRAF------WRHFGSEVWNINQDGIDILIEQRNV 266
            ...|..                     ||.:.:.      ||..|..|.......|:...|::||
 Worm   632 SNMRKSVKYTFEIVNCLKSTSLYSQGMQPVMYSMMESANGWRRVGENVCYFRNLYINENEEKKNV 696

  Fly   267 ADARKFMDKVGYSYNIMID-DIESAIDESYVEVPAVEHPLD-SVRNNSLPWMEVPGSTMNWRRYH 329
            .:.:    |..|.|:|..: ..::..|..|:   |..:|.. |..|:||       |.:..|:
 Worm   697 EEQK----KKKYYYSIRFNVTFQNTGDICYI---AYHYPYTYSFLNSSL-------SMLKKRK-- 745

  Fly   330 DQADIKQFLQTLLETYSENVELIQ--IGVTRNKRPLEVIRVSNGNPDNWAVF-----------VD 381
                            .|||...:  ||.:....|::::.::  .|.:.|..           |.
 Worm   746 ----------------QENVYCREDVIGHSLAGNPIKMLTIT--TPASAAEIAAREVIVLSARVH 792

  Fly   382 AGLQARDWLSPAALTYAISKLTHLWGRPKGKDKGEGQRQSRAEKAMRR-IDWYFLPLANPDGYQY 445
            .|.....|:....|...:.                  |||.....:|. ..:..:|:.||||.
 Worm   793 PGETNASWIMQGILENLLC------------------RQSNEMYRLRESFIFKIVPMINPDGV-- 837

  Fly   446 SRQTDRLWTKNRGYDSVSGCY-----GVNLDRNFDYGWDGTGSTSNPCKNLYRGAHSFSEPE--- 502
                            .:|.:     |::|:|.    ||      .|.:.|:        ||
 Worm   838 ----------------TNGSHRCSLAGIDLNRM----WD------RPNEALH--------PEVFA 868

  Fly   503 SRAVCSFL---SGMREYLGAYVSLGG---------YGQAITYPWGDADYVTENQRNLKQTARRAV 555
            ::|:..:|   :..:.:  |||.:.|         ||...:..|...|.:......|::...
 Worm   869 TKAIIQYLCEVANKKPF--AYVDIHGHSKKWDYFVYGNNASESWRADDVLDVGAAQLEEELH--- 928

  Fly   556 LALRRLNQAEYSS---GTSYRQKLARPGNSAD----WVQDRIGP----QLVFNMFLKDQGRYGYL 609
            |||.:..:|...|   .:..|..:.|...|:.    |.|..:..    :..|..|.|.|.. ||.
 Worm   929 LALPKALEATCPSRFNASECRFNITRAKESSARVNVWRQFGVSTAYTLESTFCGFHKGQNS-GYQ 992

  Fly   610 LPPHYIVESGEEVF-EFLRI 628
            :....:.|.|.::. .||.:
 Worm   993 INTSDLKEIGRDLLHSFLEM 1012

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42264	NP_572260.2	Propep_M14	<241..293	CDD:460505	12/58 (21%)
		Peptidase_M14	334..624	CDD:459730	60/335 (18%)
ccpp-1	NP_491674.2	Pepdidase_M14_N	589..725	CDD:407865	22/142 (15%)
		Peptidase_M14_like	749..1012	CDD:472171	60/324 (19%)