back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42264 and CPB1

DIOPT Version :9

Sequence 1:	NP_572260.2	Gene:	CG42264 / 31504	FlyBaseID:	FBgn0259149	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_001862.2	Gene:	CPB1 / 1360	HGNCID:	2299	Length:	417	Species:	Homo sapiens

Alignment Length:	512	Identity:	125/512 - (24%)
Similarity:	210/512 - (41%)	Gaps:	112/512 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 VVALFALTFVALI-----GSVF-GQKLLLWRSVSVPEISGISGLPLALLTLNSSELYESTLEGLQ 186
            ::||..|..|||.     |..| |:|:.   .|:|.:.:.|:.:         .||..:|
Human     1 MLALLVLVTVALASAHHGGEHFEGEKVF---RVNVEDENHINII---------RELASTT----- 48

  Fly   187 WLSPMDLRRFDFISPGSSYQINRRYRNGSQVQRYYGFQLWKVHETRLEQPELRAFWRHFGSEVWN 251
                    :.||..|.|..||                   |.|.|
Human    49 --------QIDFWKPDSVTQI-------------------KPHST-------------------- 66

  Fly   252 INQDGIDILIEQRNVADARKFMDKVGYSYNIMIDDIESAIDESYVEVPAVEHPLDSVRNNSLPWM 316
                 :|..::..:.......:.:....|.::|.::.:.::..:          ||
Human    67 -----VDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQF----------DS--------- 107

  Fly   317 EVPGSTMNWRRYHDQADIKQFLQTLLETYSENVELIQ---IGVTRNKRPLEVIRVSNGNPDNWAV 378
            .|..:..::.:|:....|:.:.|   :..:||..||.   ||.|...|.:.:::|.....:..|:
Human   108 RVRATGHSYEKYNKWETIEAWTQ---QVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAI 169

  Fly   379 FVDAGLQARDWLSPAALTYAISKLTHLWGRPKGKDKGEGQRQSRAEKAMRRIDWYFLPLANPDGY 443
            |:|.|..||:|:|||...:.:.:....:|           |:.:..:.:.::|:|.||:.|.|||
Human   170 FMDCGFHAREWISPAFCQWFVREAVRTYG-----------REIQVTELLDKLDFYVLPVLNIDGY 223

  Fly   444 QYSRQTDRLWTKNRGYDSVSGCYGVNLDRNFDYGWDGTGSTSNPCKNLYRGAHSFSEPESRAVCS 508
            .|:....|.|.|.|...:.|.|.|.:.:||||.||...|::.|||...|.|..:.||.|::|:..
Human   224 IYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALAD 288

  Fly   509 FLSGMREYLGAYVSLGGYGQAITYPWGDADYVTENQRNLKQTARRAVLALRRLNQAEYSSGTSYR 573
            |:......:.||:::..|.|.:.||:..|..:.||...|...|:..|..|..|:..:|:.|....
Human   289 FIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGAT 353

  Fly   574 QKLARPGNSADWVQDRIGPQLVFNMFLKDQGRYGYLLPPHYIVESGEEVFEFLRIIA 630
            ......|.|.||..|: |.:..|...|:|.||||:|||...|..:.||.|..::.:|
Human   354 TIYPAAGGSDDWAYDQ-GIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVA 409

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.