Protein Alignment CG42264 and CPB1

DIOPT Version :10

• Sequence 1: NP_572260.2
• Gene: CG42264 / 31504
• FlyBaseID: FBgn0259149
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_001862.2
• Gene: CPB1 / 1360
• HGNCID: 2299
• Length: 417
• Species: Homo sapiens
• Alignment Length: 512
• Identity: 125/512 - (24%)
• Similarity: 210/512 - (41%)
• Gaps: 112/512 - (21%)

  Fly   128 VVALFALTFVALI-----GSVF-GQKLLLWRSVSVPEISGISGLPLALLTLNSSELYESTLEGLQ 186
            ::||..|..|||.     |..| |:|:.   .|:|.:.:.|:.:         .||..:|
Human     1 MLALLVLVTVALASAHHGGEHFEGEKVF---RVNVEDENHINII---------RELASTT----- 48

  Fly   187 WLSPMDLRRFDFISPGSSYQINRRYRNGSQVQRYYGFQLWKVHETRLEQPELRAFWRHFGSEVWN 251
                    :.||..|.|..||                   |.|.|
Human    49 --------QIDFWKPDSVTQI-------------------KPHST-------------------- 66

  Fly   252 INQDGIDILIEQRNVADARKFMDKVGYSYNIMIDDIESAIDESYVEVPAVEHPLDSVRNNSLPWM 316
                 :|..::..:.......:.:....|.::|.::.:.::..:          ||
Human    67 -----VDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQF----------DS--------- 107

  Fly   317 EVPGSTMNWRRYHDQADIKQFLQTLLETYSENVELIQ---IGVTRNKRPLEVIRVSNGNPDNWAV 378
            .|..:..::.:|:....|:.:.|   :..:||..||.   ||.|...|.:.:::|.....:..|:
Human   108 RVRATGHSYEKYNKWETIEAWTQ---QVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAI 169

  Fly   379 FVDAGLQARDWLSPAALTYAISKLTHLWGRPKGKDKGEGQRQSRAEKAMRRIDWYFLPLANPDGY 443
            |:|.|..||:|:|||...:.:.:....:|           |:.:..:.:.::|:|.||:.|.|||
Human   170 FMDCGFHAREWISPAFCQWFVREAVRTYG-----------REIQVTELLDKLDFYVLPVLNIDGY 223

  Fly   444 QYSRQTDRLWTKNRGYDSVSGCYGVNLDRNFDYGWDGTGSTSNPCKNLYRGAHSFSEPESRAVCS 508
            .|:....|.|.|.|...:.|.|.|.:.:||||.||...|::.|||...|.|..:.||.|::|:..
Human   224 IYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALAD 288

  Fly   509 FLSGMREYLGAYVSLGGYGQAITYPWGDADYVTENQRNLKQTARRAVLALRRLNQAEYSSGTSYR 573
            |:......:.||:::..|.|.:.||:..|..:.||...|...|:..|..|..|:..:|:.|....
Human   289 FIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGAT 353

  Fly   574 QKLARPGNSADWVQDRIGPQLVFNMFLKDQGRYGYLLPPHYIVESGEEVFEFLRIIA 630
            ......|.|.||..|: |.:..|...|:|.||||:|||...|..:.||.|..::.:|
Human   354 TIYPAAGGSDDWAYDQ-GIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVA 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42264	NP_572260.2	Propep_M14	<241..293	CDD:460505	3/51 (6%)
		Peptidase_M14	334..624	CDD:459730	91/292 (31%)
CPB1	NP_001862.2	Propep_M14	28..104	CDD:460505	18/144 (13%)
		M14_CPB	114..413	CDD:349443	94/311 (30%)