Protein Alignment CG42264 and CPA3

DIOPT Version :10

• Sequence 1: NP_572260.2
• Gene: CG42264 / 31504
• FlyBaseID: FBgn0259149
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_001861.2
• Gene: CPA3 / 1359
• HGNCID: 2298
• Length: 417
• Species: Homo sapiens
• Alignment Length: 398
• Identity: 104/398 - (26%)
• Similarity: 190/398 - (47%)
• Gaps: 41/398 - (10%)

  Fly   241 FW-----RHFGSEVWNINQDGIDILIEQRNVADARKFMDKVGYSYNIMIDDIESAIDESYVEVPA 300
            ||     .|..:.:.      :|..:.::.....:..:|:....|.|:|.|::..|::.:
Human    51 FWYPGATHHVAANMM------VDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQF----- 104

  Fly   301 VEHPLDSVRNNSLPWMEVPGSTMNWRRYHDQADIKQFLQTLLETYSENVELIQIGVTRNKRPLEV 365
                  .|:.      ::|| ..::.:|::...|..:.:.:::.|.|.|..|:||.|....||.|
Human   105 ------DVKE------DIPG-RHSYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYV 156

  Fly   366 IRVSNGNPDNWAVFVDAGLQARDWLSPAALTYAISKLTHLWGRPKGKDKGEGQRQSRAEKAMRRI 430
            :::...|....|:|.|.|:.||:|:|||...:.:.:.|..:||.|           ...|.:.|:
Human   157 LKIGEKNERRKAIFTDCGIHAREWVSPAFCQWFVYQATKTYGRNK-----------IMTKLLDRM 210

  Fly   431 DWYFLPLANPDGYQYSRQTDRLWTKNRGYDSVSGCYGVNLDRNFDYGWDGTGSTSNPCKNLYRGA 495
            ::|.||:.|.|||.:|...:|:|.|||..:..|.|.|.:|:|||:..|:...:|::||.:.|||:
Human   211 NFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGS 275

  Fly   496 HSFSEPESRAVCSFLSGMREYLGAYVSLGGYGQAITYPWGDADYVTENQRNLKQTARRAVLALRR 560
            ...||.|::||.:|:......:..|::...|.|.:.:|:|....:..|..:|.:.|:.....|..
Human   276 APESEKETKAVTNFIRSHLNEIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLST 340

  Fly   561 LNQAEYSSGTSYRQKLARPGNSADWVQDRIGPQLVFNMFLKDQGRYGYLLPPHYIVESGEEVFEF 625
            ..:..|..|..........|:|.||..| :|.:..|...|:|:|::|:|||...|..:..|....
Human   341 RYETRYIYGPIESTIYPISGSSLDWAYD-LGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLA 404

  Fly   626 LRIIAQQL 633
            ::.||:.:
Human   405 VKFIAKYI 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42264	NP_572260.2	Propep_M14	<241..293	CDD:460505	10/56 (18%)
		Peptidase_M14	334..624	CDD:459730	88/289 (30%)
CPA3	NP_001861.2	Propep_M14	27..103	CDD:460505	10/57 (18%)
		M14_CPB	114..413	CDD:349443	91/311 (29%)