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Protein Alignment CG42264 and CPA2

DIOPT Version :9

Sequence 1:	NP_572260.2	Gene:	CG42264 / 31504	FlyBaseID:	FBgn0259149	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_001860.2	Gene:	CPA2 / 1358	HGNCID:	2297	Length:	419	Species:	Homo sapiens

Alignment Length:	436	Identity:	119/436 - (27%)
Similarity:	204/436 - (46%)	Gaps:	50/436 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   199 ISPGSSYQINRRYRNGSQVQRYYGFQLWKVHETRLEQPELRAFWRHFGSEVWNINQDGIDILIEQ 263
            |.|.:..||....:  .:.|.:.....||...|..|...:|                     :..
Human    30 IVPSNEEQIKNLLQ--LEAQEHLQLDFWKSPTTPGETAHVR---------------------VPF 71

  Fly   264 RNVADARKFMDKVGYSYNIMIDDIESAIDESYVEVPAVEHPLDSVRNNSLPWMEVPGSTMNWRRY 328
            .||...:.|::..|.:|:|||:|::..:|:...|:      |.:.|...       ....|:..|
Human    72 VNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEM------LFNRRRER-------SGNFNFGAY 123

  Fly   329 HDQADIKQFLQTLLETYSENVELIQIGVTRNKRPLEVIRVSNGNPDNWAVFVDAGLQARDWLSPA 393
            |...:|.|.:..|:..:...|..:.||.:...||:.|::.|.|. |..|:::|||:.||:|::.|
Human   124 HTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGG-DKPAIWLDAGIHAREWVTQA 187

  Fly   394 ALTYAISKLTHLWGRPKGKDKGEGQRQSRAEKAMRRIDWYFLPLANPDGYQYSRQTDRLWTKNRG 458
            ...:..:|:...:    |||..       ....:..:|.:.||:.|||||.:|:..:|:|.|.|.
Human   188 TALWTANKIVSDY----GKDPS-------ITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRS 241

  Fly   459 YDSVSGCYGVNLDRNFDYGWDGTGSTSNPCKNLYRGAHSFSEPESRAVCSFLSGMREYLGAYVSL 523
            ..|.|.|.||:.:||:|.|:.|.|::||||.:.|.|..:.||.|.:::..|:....: :.|:::|
Human   242 KVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGK-VKAFITL 305

  Fly   524 GGYGQAITYPWGDADYVTENQRNLKQTARRAVLALRRLNQAEYSSGTSYRQKLARPGNSADWVQD 588
            ..|.|.:.:|:|......::...|.:.|::|..:||.|:..:|..|..........|.|.||..|
Human   306 HSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYD 370

  Fly   589 RIGPQLVFNMFLKDQGRYGYLLPPHYIVESGEEVFEFLRIIAQQLQ 634
             .|.:..|...|:|.||||:|||...|:.:.||.:..|:.|.:.::
Human   371 -YGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVR 415

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.