DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42264 and CPO

DIOPT Version :9

Sequence 1:	NP_572260.2	Gene:	CG42264 / 31504	FlyBaseID:	FBgn0259149	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_775100.1	Gene:	CPO / 130749	HGNCID:	21011	Length:	374	Species:	Homo sapiens

Alignment Length:	326	Identity:	100/326 - (30%)
Similarity:	167/326 - (51%)	Gaps:	20/326 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   302 EHPLDSVRNNSLPW-MEVPGSTMNWRRYHDQADIKQFLQTLLETYSENVELIQIGVTRNKRPLEV 365
            :|..:.|..:..|| :|    |.::..||...:|.::::.:.|.|.|.|....:|||....|:..
Human    27 QHRQEIVDKSVSPWSLE----TYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYY 87

  Fly   366 IRVS--NGNPDNWAVFVDAGLQARDWLSPAALTYAISKLTHLWGRPKGKDKGEGQRQSRAEKAMR 428
            :::|  :|||.. .:::|.|:.||:|::||...:.:.::..     ..||      .|...|.:|
Human    88 LKISQPSGNPKK-IIWMDCGIHAREWIAPAFCQWFVKEILQ-----NHKD------NSSIRKLLR 140

  Fly   429 RIDWYFLPLANPDGYQYSRQTDRLWTKNRGYDSVSGCYGVNLDRNFDYGWDGTGSTSNPCKNLYR 493
            .:|:|.||:.|.|||.|:..|||||.|:|...:...|:|.:|:|||:..|...|::.|.....:.
Human   141 NLDFYVLPVLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFC 205

  Fly   494 GAHSFSEPESRAVCSFLSGMREYLGAYVSLGGYGQAITYPWGDADYVTENQRNLKQTARRAVLAL 558
            |....||||::||.||:...::.:..::::..|||.|..|:|.....:.|...:.|..::|..||
Human   206 GTGPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANAL 270

  Fly   559 RRLNQAEYSSGTSYRQKLARPGNSADWVQDRIGPQLVFNMFLKDQGRYGYLLPPHYIVESGEEVF 623
            :......|..|:|.....|..|:|.||.:| ||....:...|:|.|.||::||...|..:.||..
Human   271 KAKYGTNYRVGSSADILYASSGSSRDWARD-IGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETM 334

  Fly   624 E 624
            |
Human   335 E 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42264	NP_572260.2	Propep_M14	<241..293	CDD:280416
CG42264	NP_572260.2	M14_CP_A-B_like	328..633	CDD:199844	94/299 (31%)
CPO	NP_775100.1	M14_CPO	47..344	CDD:133105	94/302 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157742
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.850