DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42264 and AGBL1

DIOPT Version :9

Sequence 1:	NP_572260.2	Gene:	CG42264 / 31504	FlyBaseID:	FBgn0259149	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_001373023.1	Gene:	AGBL1 / 123624	HGNCID:	26504	Length:	1121	Species:	Homo sapiens

Alignment Length:	227	Identity:	48/227 - (21%)
Similarity:	74/227 - (32%)	Gaps:	68/227 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 EVVALFALTFVALIGSVFGQKLL--LW------RSVSVPEISGISGLPLALLTLNSSELYESTLE 183
            |:.||.....:|......||.||  ||      .|||:..:.||:|....|..:
Human    97 ELEALDVTLILARKNLSHGQNLLHCLWALRVFASSVSMGAMLGINGAMELLFKV----------- 150

  Fly   184 GLQWLSPMDLRRFDFISPGS--------SYQINRRYRNGSQVQRYYGF-QLWKVHETRLEQPELR 239
                ::|...:|...|...:        |....||..|...|....|. |.|..|:|.....::|
Human   151 ----ITPYTRKRTQAIRAATEVLAALLKSKSNGRRAVNRGYVTSLLGLHQDWHSHDTANAYVQIR 211

  Fly   240 AFWRHFGSEVWNINQDGIDILIEQRNVADARK----FMDKVGYSYNIMIDDIESAIDESYVEVPA 300
            .                 .:|:..|::|..|.    |:...|  ..|:....::.:|:..:| |.
Human   212 R-----------------GLLLCLRHIAALRSGREAFLAAQG--MEILFSTTQNCLDDKSME-PV 256

  Fly   301 VE------------HPLDSVRNNSLPWMEVPG 320
            :.            .||..|..:|.....|||
Human   257 ISVVLQILRQCYPTSPLPLVTASSAYAFPVPG 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42264	NP_572260.2	Propep_M14	<241..293	CDD:280416	7/55 (13%)
CG42264	NP_572260.2	M14_CP_A-B_like	328..633	CDD:199844
AGBL1	NP_001373023.1	Pepdidase_M14_N	596..730	CDD:407865
AGBL1	NP_001373023.1	M14_Nna1	754..1019	CDD:349477
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900