DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3097 and CPA5

DIOPT Version :9

Sequence 1:NP_572259.1 Gene:CG3097 / 31503 FlyBaseID:FBgn0029804 Length:445 Species:Drosophila melanogaster
Sequence 2:NP_001120913.1 Gene:CPA5 / 93979 HGNCID:15722 Length:436 Species:Homo sapiens


Alignment Length:450 Identity:140/450 - (31%)
Similarity:223/450 - (49%) Gaps:53/450 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 QKTMLLQLLLLVAA----------VAASLANELPSNLTLLDANE--IPQRYDEAQLWRIYNISEA 55
            ::|:|:...:|.||          |...||.: ...|:||...|  .||:.|   .||     ..
Human    18 RRTLLVFSFILAAALGQMNFTGDQVLRVLAKD-EKQLSLLGDLEGLKPQKVD---FWR-----GP 73

  Fly    56 MQKRVPVGQMLEQKFGGNIWKENSKFLDISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDEEL 120
            .:..:||                    |:.:...:||..:::|.:|.|...|:..:||.::||| 
Human    74 ARPSLPV--------------------DMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEE- 117

  Fly   121 LEGIQSSSFGHGRRTKKAARSSMHWKDYHDLETIYSFMREIRTKFPNIVRLYTIGQTAEGRDLKV 185
                 ..:....||.:::. :|..:..||.||.|||::.....:..:||....||.:.|.:.:.|
Human   118 -----RQAMAKSRRLERST-NSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILV 176

  Fly   186 LRISENPRENKKVWIDGGIHAREWISPATVTFILYQLMSDWENQPA---HIRGLTWYIMPVMNPD 247
            |:.|.....:..:|||.|||:||||:.||..:...:::||:.....   .:..:..:|..|.|||
Human   177 LKFSTGGSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPD 241

  Fly   248 GYEYSRTTNRLWRKNRSPSRRAQCSGVDLNRNFDIGWNGYGSSTNPCSDTYRGSAPASERETRAV 312
            |:.::.:.|||||||:|......|.|||||||:..|:.|.||::||||:||.|.:|.||.|..|:
Human   242 GFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAI 306

  Fly   313 AEFLAKRKYNLESYLTFHSYGQMIVYPWAYKAVKVKDASVLQRVSSLAAERILQKTGTSYRAAVT 377
            ..|:.... |.::.::.|||.||::||:......|.:...|..::..|.|.:.:..|..|.....
Human   307 VNFITAHG-NFKALISIHSYSQMLMYPYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEYIFGSI 370

  Fly   378 HEVLGIAGGGSDDWSRAALGVKYVYTIELRDRGAYGFVLPPRFIKDTALEGWTVVETVAQ 437
            ...|.:|.|.:.||:..: |:||.::.||||.|.|||:||...|..||.|.|..:.|:.:
Human   371 STTLYVASGITVDWAYDS-GIKYAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIME 429

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
CG3097NP_572259.1 Propep_M14 64..118 CDD:280416 9/53 (17%)
M14_CP_A-B_like 148..439 CDD:199844 106/292 (36%)
CPA5NP_001120913.1 Propep_M14 43..117 CDD:308061 23/102 (23%)
Peptidase_M14_like 134..434 CDD:325013 106/297 (36%)
Substrate binding. /evidence=ECO:0000250|UniProtKB:P00730 196..199 1/2 (50%)