DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3097 and Agbl3

DIOPT Version :9

Sequence 1:	NP_572259.1	Gene:	CG3097 / 31503	FlyBaseID:	FBgn0029804	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_001276585.1	Gene:	Agbl3 / 76223	MGIID:	1923473	Length:	1006	Species:	Mus musculus

Alignment Length:	421	Identity:	75/421 - (17%)
Similarity:	134/421 - (31%)	Gaps:	142/421 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 ELPSNLTLLDANEIPQRYDEAQLWRIYNISEAMQKRV---PVGQMLEQKFGGNIWKENSKFLDIS 85
            |:....|:::..:....|:.......|:..||....:   .:|..::. :..|:.::...|..::
Mouse   223 EIVYRFTIVNFTKPASLYNRGMKPLFYSEKEAKTHNIGWQRIGDQIKY-YKNNLGQDGRHFFSLT 286

  Fly    86 IARDQLKAARSFLSAHRLDPQILSH-------NIQSMIDEELLEGIQSSSFGHGRRTKKAARSSM 143
                     .:|...|..|....:|       |:|     |.|.||.|.
Mouse   287 ---------WTFQFPHSQDTCYFAHCYPYTYSNLQ-----EYLSGINSD---------------- 321

  Fly   144 HWKDYHDLETIYSFMREIRTKF-----------PNIVRLYTIGQTAEGRDLKVLRISENPRENKK 197
                            .:|:||           .|:|.:.||        ...|:.|::.|  |.
Mouse   322 ----------------PVRSKFCKIRVLCHTLARNMVYVLTI--------TTPLKTSDSKR--KA 360

  Fly   198 VWIDGGIHARE----WISPATVTFIL-----YQLMSDWENQPAHIRGLTWYIMPVMNPDGYEYSR 253
            |.:...:|..|    ||....:.:||     .:|:.|         ...:.::|::||||....
Mouse   361 VILTARVHPGETNSSWIMKGFLDYILGDSSDARLLRD---------TFIFKVVPMLNPDGVIVG- 415

  Fly   254 TTNRLWRKNRSPSRRAQCSGVDLNRNFDIGWNGYGSSTNPCSDTYRGSAPASERETRAVAEFLAK 318
                        :.|...:|.|||||:              :...:.|.|:.......:...:.|
Mouse   416 ------------NYRCSLAGRDLNRNY--------------TSLLKESFPSVWYTRNMINRLMEK 454

  Fly   319 RKYNLESYLTFHSYGQMIVYPWAY-----KAVKVKDASVLQRVSSLAAER----ILQKTGTSYRA 374
            |:..|...|..||..|.|   :.|     ...|.|...:.||:..|...:    |...:...:..
Mouse   455 REVILYCDLHGHSRKQNI---FMYGCDGSSRSKTKGLYLQQRIFPLMLSKNCPNIFSFSACKFNV 516

  Fly   375 AVTHEVLGIAGGGSDDWSRAALGVKYVYTIE 405
            ..:.|    ..|....|.   :|::..:|:|
Mouse   517 QKSKE----GTGRVVMWK---MGIRNSFTLE 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3097	NP_572259.1	Propep_M14	64..118	CDD:280416	8/60 (13%)
CG3097	NP_572259.1	M14_CP_A-B_like	148..439	CDD:199844	55/287 (19%)
Agbl3	NP_001276585.1	M14_AGBL2-3_like	315..576	CDD:133117	59/314 (19%)
Agbl3	NP_001276585.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	790..810
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900