DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3097 and AGBL5

DIOPT Version :9

Sequence 1:	NP_572259.1	Gene:	CG3097 / 31503	FlyBaseID:	FBgn0029804	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_068603.4	Gene:	AGBL5 / 60509	HGNCID:	26147	Length:	886	Species:	Homo sapiens

Alignment Length:	148	Identity:	33/148 - (22%)
Similarity:	61/148 - (41%)	Gaps:	36/148 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 LETIYSFMRE--------IRTKFPNIVRLYTIGQTAEGRDLKVLRISENPR----ENKKV-WIDG 202
            |:||| :.||        :|.....|...:.:.:..|.|..::...:..||    ..|:: ::..
Human   186 LDTIY-YHRELLCYSLDGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPFRFAGKRIFFLSS 249

  Fly   203 GIHAREWISPATVT---FILYQLMSDWENQPAHIRGLTWYIMPVMNPDGY--EYSRTTNRLWRKN 262
            .:|..|  :|::..   |:.:.|..|........|...:.::|::||||.  .:.||.:|
Human   250 RVHPGE--TPSSFVFNGFLDFILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRGHYRTDSR----- 307

  Fly   263 RSPSRRAQCSGVDLNRNF 280
                      ||:|||.:
Human   308 ----------GVNLNRQY 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3097	NP_572259.1	Propep_M14	64..118	CDD:280416
CG3097	NP_572259.1	M14_CP_A-B_like	148..439	CDD:199844	33/148 (22%)
AGBL5	NP_068603.4	M14_AGBL5_like	176..568	CDD:199860	33/148 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	344..364
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	605..734
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	784..848
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810