DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3097 and CG8562

DIOPT Version :9

Sequence 1:	NP_572259.1	Gene:	CG3097 / 31503	FlyBaseID:	FBgn0029804	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_648118.1	Gene:	CG8562 / 38828	FlyBaseID:	FBgn0035779	Length:	424	Species:	Drosophila melanogaster

Alignment Length:	449	Identity:	142/449 - (31%)
Similarity:	220/449 - (48%)	Gaps:	44/449 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 MLLQLLLLVAAVAASLANELPSNLTLLDANEIPQRYDEAQLWRIYNISEAMQKRVPVGQMLEQ-K 69
            |...|.|||..:.|:|.           |.|  |.|:.      |.|.|.:........:|.| .
  Fly     1 MKFSLGLLVLFLGATLV-----------AAE--QDYEG------YRIYEVIPSTADQADLLHQLS 46

  Fly    70 FGGNIWKENSKFLD----ISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDEEL----LEGIQS 126
            ..|..:...::.|.    :.::..|||..:..:.|.::...:::.|:.:.|.||.    ::.:.:
  Fly    47 LQGYDFISETRLLGHPSRVIVSPAQLKHFQQLVEAEKMTLTLVNSNLGASIAEEFAQRQMQRLLA 111

  Fly   127 SSFGHGRRTKKAARSSMHWKDYHDLETIYSFMREIRTKFPNIVRLYTIGQTAEGRDLKVLRISE- 190
            ...|.||         :..:.|:..|.|.:::.::..:||:.|.:.|:|.:.|.|.||.:.|:.
  Fly   112 PITGKGR---------LSTERYYTHEEIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNG 167

  Fly   191 NPRENKKV-WIDGGIHAREWISPATVTFILYQLMSDWENQPAHIRGLTWYIMPVMNPDGYEYSRT 254
            :.:.|||| ::|||.|||||||||.|.:::.||:..:|.....::...|.|:|::|.||||:::|
  Fly   168 DGKANKKVIFMDGGFHAREWISPAAVLYVIDQLVEQFEENAHLLKDYDWVILPLVNADGYEHTQT 232

  Fly   255 TN--RLWRKNRSPSRRA--QCSGVDLNRNFDIGWNGYGSSTNPCSDTYRGSAPASERETRAVAEF 315
            ..  |:|||.|.|...|  .|.|.|.|||||..||..|:|:|||:|||.|....||.||..|.:.
  Fly   233 GTLARMWRKTRQPYTYAGQTCYGADPNRNFDFHWNEEGASSNPCADTYAGPTAFSEPETITVRDL 297

  Fly   316 LAKRKYNLESYLTFHSYGQMIVYPWAYKAVKVKDASVLQRVSSLAAERILQKTGTSYRAAVTHEV 380
            :.........|||.||||..::|||.:.:...::...|..|:...||.|...|||.|....:..|
  Fly   298 MHSLADRGIMYLTLHSYGNYLLYPWGWTSDLPENWEDLDAVARTGAEAIENATGTVYTYGSSTNV 362

  Fly   381 LGIAGGGSDDWSRAALGVKYVYTIELRDRGAYGFVLPPRFIKDTALEGWTVVETVAQAI 439
            |.||.|.|||:...| |.....|:||...|:.||..|...|.:...|.|..:..:|:.:
  Fly   363 LYIAAGASDDYGYYA-GFNVSITMELPGAGSIGFNPPVTRIDEFVTETWIGIRAMAEKV 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3097	NP_572259.1	Propep_M14	64..118	CDD:280416	10/58 (17%)
CG3097	NP_572259.1	M14_CP_A-B_like	148..439	CDD:199844	113/296 (38%)
CG8562	NP_648118.1	Propep_M14	30..99	CDD:280416	11/68 (16%)
CG8562	NP_648118.1	M14_CP_A-B_like	124..420	CDD:199844	113/296 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466933
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.850