DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3097 and Agbl2

DIOPT Version :9

Sequence 1:	NP_572259.1	Gene:	CG3097 / 31503	FlyBaseID:	FBgn0029804	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_848870.2	Gene:	Agbl2 / 271813	MGIID:	2443254	Length:	862	Species:	Mus musculus

Alignment Length:	189	Identity:	40/189 - (21%)
Similarity:	69/189 - (36%)	Gaps:	56/189 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 IRTKFPNIVRLYTIGQTAEGRDLKVLRI---SENPRE---NKKVWIDGGIHARE----WISPATV 215
            |:::|   .:|..:.::..|..:.:|.|   |..|:|   .|.|.:...:|..|    ||....:
Mouse   378 IQSQF---CKLRALCRSLAGNTVYLLTITNPSRTPQEAAAKKAVVLSARVHPGESNSSWIMNGFL 439

  Fly   216 TFIL-----YQLMSDWENQPAHIRGLTWYIMPVMNPDGYEYSRTTNRLWRKNRSPSRRAQCSGVD 275
            .|||     .||:.|.         ..:.::|::||||....             :.|...:|.|
Mouse   440 DFILSNSPDAQLLRDI---------FVFKVIPMLNPDGVIVG-------------NYRCSLAGRD 482

  Fly   276 LNRNFDIGWNGYGSSTNPCSDTYRGSAPASERETRAVAEFLAKRKYNLESYLTFHSYGQ 334
            |||::              ....:.|.|........:...|.:|:..|  |..||.:.:
Mouse   483 LNRHY--------------KTVLKDSFPCIWYTKNMIKRLLEEREVLL--YCDFHGHSR 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3097	NP_572259.1	Propep_M14	64..118	CDD:280416
CG3097	NP_572259.1	M14_CP_A-B_like	148..439	CDD:199844	40/189 (21%)
Agbl2	NP_848870.2	Pepdidase_M14_N	231..358	CDD:375499
		M14_AGBL2-3_like	379..629	CDD:349478	39/188 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	669..692
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	704..728
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	750..836
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900