DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3097 and cpa5

DIOPT Version :9

Sequence 1:	NP_572259.1	Gene:	CG3097 / 31503	FlyBaseID:	FBgn0029804	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_954965.1	Gene:	cpa5 / 246092	ZFINID:	ZDB-GENE-020514-1	Length:	419	Species:	Danio rerio

Alignment Length:	447	Identity:	145/447 - (32%)
Similarity:	239/447 - (53%)	Gaps:	55/447 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 QLLLLVAAVAASLANELPSNLTLLDANEI----PQRYDEAQLWRIYNISEAMQKRVPVGQMLEQK 69
            :||:|:|...|....:      ..:.:::    |:  ||||:..:..::|.       |:.|
Zfish     3 RLLVLIALFVAVFGKK------TFEGDQVFRITPK--DEAQIDLLKELTEE-------GEHL--- 49

  Fly    70 FGGNIWKE---NSKFLDISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDEELLEGIQSSSFGH 131
             |.::|.|   .|..||:.:....|:|.|:||:.:::...|:..|:|.::|:|..:.:
Zfish    50 -GLSVWMEPILESLPLDLHVPFHSLQAVRAFLAYNQIPYHIMIENVQELLDDEQRDMV------- 106

  Fly   132 GRRTKKAARSS--MHWKDYHDLETIYSFMREIRTKFPNIVRLYTIGQTAEGRDLKVLRISENPRE 194
              :.:..|||:  ..:..||||.:|.|||..:..:..|:|....|||:.|.|.|.||:.|.. ..
Zfish   107 --KYRGLARSTDDFVYTTYHDLNSINSFMDMLVAENRNMVSKVVIGQSYEKRPLNVLKFSTG-AN 168

  Fly   195 NKKVWIDGGIHAREWISPATVTFILYQLMSDWENQPAHIRGLT-------WYIMPVMNPDGYEYS 252
            ...:|||.|||:|||::.|:..:...:::.|:...|.    ||       .::..|.||||:.|:
Zfish   169 RPGIWIDTGIHSREWVTQASGVWFAKKIVKDYGRDPV----LTDILNSHDIFLEIVTNPDGFVYT 229

  Fly   253 RTTNRLWRKNRSPSRRAQCSGVDLNRNFDIGWNGYGSSTNPCSDTYRGSAPASERETRAVAEFLA 317
            .|.:|:|||.|.|:..:.|.|||.|||:|.|:.|.|||.|||::||||.:..||.|.:|:.:|:
Zfish   230 HTKDRMWRKTRKPNPGSSCVGVDPNRNWDAGFGGGGSSNNPCTETYRGPSAHSEPEVKAIVDFV- 293

  Fly   318 KRKYNLESYLTFHSYGQMIVYPWAYKAVKVKDASVLQRVS--SLAAERILQKTGTSYRAAVTHEV 380
            |....::::::.|||.||::||:.|.....||.:.|..|:  ::.:.:.|..|..:|.:.:|  .
Zfish   294 KSHGKIKAFVSIHSYSQMLLYPYGYTYTAAKDKAELHEVARKAITSLQSLYNTRYTYGSIIT--T 356

  Fly   381 LGIAGGGSDDWSRAALGVKYVYTIELRDRGAYGFVLPPRFIKDTALEGWTVVETVAQ 437
            :..|.||:.||:... |:||.||.||||.|.|||:||...|..||.|.|..:..:.:
Zfish   357 IYQASGGTIDWTYNQ-GIKYSYTFELRDTGRYGFILPANQIVPTAEETWLALMAIME 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3097	NP_572259.1	Propep_M14	64..118	CDD:280416	15/56 (27%)
CG3097	NP_572259.1	M14_CP_A-B_like	148..439	CDD:199844	113/299 (38%)
cpa5	NP_954965.1	Propep_M14	27..100	CDD:280416	22/85 (26%)
cpa5	NP_954965.1	Peptidase_M14_like	118..417	CDD:299699	113/304 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593418
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm6426
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.750