DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3097 and W01A8.6

DIOPT Version :9

Sequence 1:	NP_572259.1	Gene:	CG3097 / 31503	FlyBaseID:	FBgn0029804	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_492003.2	Gene:	W01A8.6 / 189076	WormBaseID:	WBGene00012168	Length:	380	Species:	Caenorhabditis elegans

Alignment Length:	334	Identity:	109/334 - (32%)
Similarity:	174/334 - (52%)	Gaps:	37/334 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 YHDLETIYSFMREIRTKFPNIVRLYTIGQTAEGRDLKVLRISENPRENKK---VWIDGGIHAREW 209
            |:|......:::.:....|:.|:|.|||:|.|||.|..:||.:.....|:   ||:|||.|||||
Worm    35 YNDWPQFEDYIKGVAHDNPSFVQLKTIGRTREGRPLLGVRIGKPALPGKRKIAVWLDGGNHAREW 99

  Fly   210 ISPATVTFILYQLMSDW---ENQPAHIRGLTWYIMPVMNPDGYEYSRTTNRL----WRKNRSPSR 267
            .:.....:.:.:|::.:   :....::..|..|:.||:||||:.||||:.|.    |||||:|..
Worm   100 PAFHVAVYFIEKLVNGYLSDDKITKYVETLDIYVFPVLNPDGFVYSRTSTRAMIRQWRKNRAPEN 164

  Fly   268 RAQ---------CSGVDLNRNFDIGWN--GYGSSTNPCSDTYRGSAPASERETRAVAEFLAKRKY 321
            ...         |.|||||||:|||::  .| ...|||||.::|..|.||.|||||.:|:...:.
Worm   165 CTGTGPFQTDICCEGVDLNRNYDIGFSHKNY-PFNNPCSDEFQGPRPFSEPETRAVRDFIMSSEI 228

  Fly   322 --NLESYLTFHSYGQMIVYPWAY-KAVKVKDASVLQRVSSLAAERILQKTGTSYRAAVTHEVLGI 383
              .|.:.::.|::||:.:.|:.| |....:|...|:.:::.||:|:.....|.||.....::||.
Worm   229 YGRLYALVSMHTHGQLWILPYNYQKRTYPQDIKDLEILANRAADRVFAYRETKYRVGTAADMLGT 293

  Fly   384 AGGGSDDWSRAALGVKYVYTIELRD--RGAYGFVLPPRFIKDTALEGWTVVETV----------A 436
            |.||:.||.:.....||||.:||..  :..:.|.:.|.::.....|.|..:|.:          .
Worm   294 ATGGATDWIKKNTPTKYVYVLELPPDMKTWFAFQVKPHWLIPIGKETWLGIEVIFDQVVEETKNF 358

  Fly   437 QAIGPSSSG 445
            |...|:::|
Worm   359 QPTEPTTNG 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3097	NP_572259.1	Propep_M14	64..118	CDD:280416
CG3097	NP_572259.1	M14_CP_A-B_like	148..439	CDD:199844	107/326 (33%)
W01A8.6	NP_492003.2	Zn_pept	35..337	CDD:214748	103/302 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920