DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3097 and ZC434.9

DIOPT Version :9

Sequence 1:	NP_572259.1	Gene:	CG3097 / 31503	FlyBaseID:	FBgn0029804	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_001251356.1	Gene:	ZC434.9 / 172908	WormBaseID:	WBGene00013895	Length:	720	Species:	Caenorhabditis elegans

Alignment Length:	483	Identity:	154/483 - (31%)
Similarity:	252/483 - (52%)	Gaps:	79/483 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 TQKTMLLQLLLLVAAVAASLANELPSNLTLLDANEIPQRYDEAQLWRIYNISEAMQKRVPVGQML 66
            |:.|:.|.:|:...|:.|.:|::.|....:|.|:..    |..||..:.:|.|..|..:
Worm     6 TRNTLWLLILISAFAINAEIADDKPPKFQVLRAHAT----DVPQLKALRDIHERTQHDL------ 60

  Fly    67 EQKFGGNIWKENSKF---LDISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDEE--------- 119
                  :.|:..||.   .||.:..|:::...|.|....:...::..::..:|.|:
Worm    61 ------DFWQTPSKVGHRADIMVDEDRMEWLDSVLKNSNISYDVIIEDVGKLILEKEHGPPRFSN 119

  Fly   120 LL-------EGIQSSSFGHGRRTKKAARSSMHWKDYHDLETIYSFMREIRTKFPNIVRLYTIGQT 177
            ||       ||...:.:|.|              :||..:||..:|::|..|:|:..:::|:|.|
Worm   120 LLFSKRMHNEGGNRARYGFG--------------EYHSYQTICDWMKDIERKYPDKAKVFTMGTT 170

  Fly   178 AEGRDLKVLRI-SENPRENKKV-WIDGGIHAREWISPATVTFILYQLMSDWENQP---AHIRGLT 237
            :|||.::.::| |:..|.:|:: |||||||||||.:..|..:.:.:|::|:.:..   |.:..|.
Worm   171 SEGRPIQGIKIGSQVWRNDKRIFWIDGGIHAREWAAVHTALWFIDRLIADYNDDSLVRAAVDRLN 235

  Fly   238 WYIMPVMNPDGYEYSRT----TNRLWRKNRSP--------SRRAQCSGVDLNRNFDIGWNGYGSS 290
            :||:||.|||||||||:    ..|||||||:.        .|...|.|||||||:|..:...|||
Worm   236 FYILPVANPDGYEYSRSDVSPMIRLWRKNRAGVVCKKDRWFRDRCCGGVDLNRNYDWHFGETGSS 300

  Fly   291 TNPCSDTYRGSAPASERETRAVAEFLAKRKYN--LESYLTFHSYGQMIVYPWAYKAVKV-KDASV 352
            |:.||:.|:||:..||.|||::.:||...:.|  :::::|.|:|.||.::|:::....| .|.:.
Worm   301 TDKCSEIYQGSSAFSESETRSMRDFLTSSELNGKIDAFITLHTYSQMWIHPYSHARKSVPADVAE 365

  Fly   353 LQRVSSLAAERILQKTGTSYRAAVTHEVLGIAGGGSDDWSRAALGVKYVYTIELR------DRGA 411
            ||||...|...:....||.|:.....::|..:.||||||::..|.:||||.:|||      |
Worm   366 LQRVGRAAVAALENTYGTKYKFGTGSDILYPSAGGSDDWAKGTLRIKYVYLLELRPGEDVWD--- 427

  Fly   412 YGFVLPPRFIKDTALEGWTVVETVAQAI 439
             ||:|....:..||.|.|..::.|.:|:
Worm   428 -GFILDQHQLIPTAKETWNGIKVVIRAV 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3097	NP_572259.1	Propep_M14	64..118	CDD:280416	9/56 (16%)
CG3097	NP_572259.1	M14_CP_A-B_like	148..439	CDD:199844	121/316 (38%)
ZC434.9	NP_001251356.1	Propep_M14	45..111	CDD:366995	15/77 (19%)
		M14_CP_A-B_like	141..454	CDD:349433	121/316 (38%)
		ShK	682..719	CDD:366702
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	232	1.000	Inparanoid score	I2182
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8411
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R17097
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.100