DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3097 and suro-1

DIOPT Version :9

Sequence 1:	NP_572259.1	Gene:	CG3097 / 31503	FlyBaseID:	FBgn0029804	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_492177.2	Gene:	suro-1 / 172557	WormBaseID:	WBGene00011235	Length:	664	Species:	Caenorhabditis elegans

Alignment Length:	499	Identity:	163/499 - (32%)
Similarity:	239/499 - (47%)	Gaps:	94/499 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KTMLLQL--LLLVAAVAASLANELPSNLTLLDANEIPQRY--------DEAQLWRIYNISEAMQK 58
            |::||.:  :|||.:|..|           .|.:....:|        ||..|..|..:
Worm     6 KSILLAVHTILLVGSVCCS-----------TDVHNTDDKYALIHVSAHDEQSLHLIKQL------ 53

  Fly    59 RVPVGQMLEQKFGGNIWKENSKF---LDISIARDQLKAARSFLSAHRLDPQILSH-NI---QSMI 116
                 |:.:.|:..:.||..|..   .||.:.|.:         :.|:..||||. |:   .|:.
Worm    54 -----QLNDFKYDLDFWKSPSSISDKADIMVKRGK---------SERMLRQILSFANVTVSMSVP 104

  Fly   117 DEELL----EGIQSSS-FGHGRRTK--------------------KAARSSMHWKDYHDLETIYS 156
            |.|.|    ||..|.| .|.|..:|                    ...::...:.||.....:..
Worm   105 DVEKLIMRNEGTTSKSHLGFGSLSKWLHDDPILDSEPDLDLTKVGALKKAKYPFGDYASYADMVK 169

  Fly   157 FMREIRTKFPNIVRLYTIGQTAEGRDLKVLRISENPRENKK-VWIDGGIHAREWISPATVTFILY 220
            :||.|...:|.|.::..||.|.||:.::.|:|.......|: ||:||.||||||.|..|..:.:.
Worm   170 YMRTIEFYYPRIAKIVRIGATHEGKPIEGLKIGARSSHKKRAVWVDGNIHAREWASSHTALYFIN 234

  Fly   221 QLMSDWENQPA---HIRGLTWYIMPVMNPDGYEYSRT----TNRLWRKNRSP--------SRRAQ 270
            ||:|::.....   ::..|.:||:|.:|||||||:||    |.|||||||||        .....
Worm   235 QLVSEYGKDAQITNYVDTLDFYIVPCLNPDGYEYTRTSPIPTVRLWRKNRSPELCRPSLWGGEKC 299

  Fly   271 CSGVDLNRNFDIGWNGYGSSTNPCSDTYRGSAPASERETRAVAEFLA--KRKYNLESYLTFHSYG 333
            |.||||||||...|...|||..|||:.|.|....||.|||||..|||  :.|..:::::|.|||.
Worm   300 CRGVDLNRNFRFHWAERGSSYEPCSNIYHGEEVFSEPETRAVRNFLATPEMKDRVDAFVTLHSYA 364

  Fly   334 QMIVYPWAYKAVKV-KDASVLQRVSSLAAERILQKTGTSYRAAVTHEVLGIAGGGSDDWSRAALG 397
            |:.:||::::.... :|...|::.:..|..|:.:..||:||.....:.|..|.||||||:::||.
Worm   365 QLWIYPYSHEEQNYPEDIGELRKTARKAINRLSRVYGTNYRMGTGADTLSPAAGGSDDWAKSALN 429

  Fly   398 VKYVYTIELRDRG--AYGFVLPPRFIKDTALEGWTVVETVAQAI 439
            |||||.||||.:.  :.||:|..:.:..||:|.:.....|..|:
Worm   430 VKYVYLIELRPQMELSNGFILHKKELIPTAVETFEGFREVVDAV 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3097	NP_572259.1	Propep_M14	64..118	CDD:280416	15/60 (25%)
CG3097	NP_572259.1	M14_CP_A-B_like	148..439	CDD:199844	122/311 (39%)
suro-1	NP_492177.2	Propep_M14	39..110	CDD:280416	21/90 (23%)
		M14_CP_A-B_like	161..473	CDD:199844	122/311 (39%)
		ShK	620..657	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8411
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.920